BSSPLUS眼内灌注在玻璃体手术中的应用评价

BSSPLUS　　　　　　510060:BSSPLUS。:138(144),BSSPLUSBSS,:3,。:BSSPLUSBSS,(t=5.183,P0.05);(χ2=1.677,P0.05);,,BSSPLUSBSS,(χ2=4.711,P0.05)。:BSSPLUS,,。:BSSPLUS　　IntraocularirrigationwithBSSPLUSinparsplanavitrectomyMAJin,GAORulong,WUDezhen,ZHANGShaochong,LIChunfangZhongshanOphthalmicCenter,ZhongshanUniversity,Guangzhou510060,ChinaObjective:ToevaluatetheclinicalvalueofintraocularirrigationwithBSSPLUSinvitrectomy.Methods:144eyesof138casesofparsplanavitrectomywereirrigatedwithdifferentintraocularsolutions,BSSPLUSorBSS(madeinourhospital).Thestatusofcornealendothelialcellsandpostoperativeintraocularinflammationsbetweenthetwosolutionswerecomparedat1dayaftersurgery,andthestatusoflenswereobservedthrough3monthsfollow-up.Results:ThelossofcornealendothelialcellsinBSSPLUSgroupwaslessthanthoseinBSSgroup(P0.05).Therewasnosignificantdif-ferenceinpostoperativeinflammationbetweenthetwogroups,however,indiabeticcases,thepostoperativeintraocularinflammationinBSSPLUSgroupwaslessthanthatinBSSgroup(χ2=4.771,P0.05).Conclusions:BSSPLUSisamoresuitableintraocularirrigatingsolutionthanthatmadeinourhospital.Ithaslessharmtothecornealen-dothelialcellsandlesspostoperativeinflammation.Keywords:BSSPLUS,Intraocularirrigation,Parsplanavitrectomy　　,、。,,。,、(),,。,。,PH,BSSPLUS(Alcon)1982,BSSPLUS,。BSS(),:1.:138(144),64,72,46～68(52.6±12.16)15(15),123(129),。,:(age-relatedmaculardegregation,AMD),(retinalvasculitis,RV)、(macularepiretinalmem-brane,MERM)、(diabeticretinopathy,DR)、(rdinalvaseularoc-·414·21(2003)6clusion,RVR)。,(BSSPLUS)(BSS)。,(1,2)。　　1　()AMDRVMERMBSS1236BSSPLUS342946515χ20.0140.0000.313P0.050.050.05　　2　()RVBRVRDRAMDMERMBSS9228161166BSSPLUS633314763155613018129χ20.5310.031.2820.0740.829P0.050.050.050.050.05　　2.:,MERMDR。,1。,。,。3.:(1)():,(KonanSP6000)。(2)():3,。(3):()()。〔1〕:(2mm×1mm):0———;+———5～10;———11～20;—21～50;———51。4.:SPSS10.0t、χ2。　　1.():,(t=0.749,P0.05);(F=0.01,P0.05);t,BSSPLUSBSS(t=5.183,P0.05)。(3)。　　3　、()(/mm2)1(/mm2)1302553.11986567.12453158.52509.2649.33502361.41986.1375.3BSSPLUS4301810.31179.3630.96201433.11117.6315.57452665.91992.1673.88202094.01693.8400.21503158.22093.81064.42452094.11069.110153302698.31441.21257.1BSS4452661.31742.6918.75502040.51058.2982.36202136.51461.4675.17251874.31101.1773.2　　2.():3,。320(27.8%),14(20%),,(χ2=1.179,P0.05)。3.():319,BSSPLUS20～95(45.6±12.4),BSS20～110(42.5±11.2),(t=2.21,P0.05)。(χ2=1.677,P0.05)(4)。　　4　0+BSSPLUS46(74.2%)16(25.8%)62BSS38(63.3%)22(36.7%)608438122χ2=1.677,P0.05　　,,,(5)。·415·21(2003)6　　5　RVDRAMDMERM0+65208648114691381013101129211414914χ20.0534.7110.156＊P0.050.050.050.05　　＊—DR(χ2=4.711,P0.05),。　　,,,。、。,,。BSSPLUSBSS、、,,。BSSPLUS,。,Joussen〔2〕,,,BSSPLUS;Nuyts〔3〕,,BSSPLUS,,。Ander-son〔4〕。,BSSPLUS〔5〕。BSSPLUSERGb,〔6〕。Araie〔7〕BSSPLUS,RPE-SH,,RPE,—,BSSPLUS,。:1.:,,。,BSSPLUS。,(、),,,,。,“”,BSSPLUS,。2.:BSSPLUSBSS,,,BSSPLUS。3.:-。Stoldt〔8〕74,,BSSPLUS。Manzanas〔9〕、,,BSSPLUS,。,-,、,。(),,BSSPLUS,,。,·416·21(2003)6。,,,DR,BSS,BSSPLUS。,,—,,,,。“”BSSPLUS,。BSSPLUS,、,,,,。〔1〕,..:　1998　186～187〔2〕JoussenAM,BarthU,CubukH,etal.Effectofirrigatingsolutionandirrigationtemperatureonthecorneaandpupilduringphacoemulsi-fication.JCataractRefractSurg　2000　26(3):392～397〔3〕Nuyts,RM,Edelhauser,HF;Holley,GP.Intraocularirrigatingsolutions:acomparisonofHartmann′slactatedRinger′ssolution,BSSandBSSPlus.Graefes-Arch-Clin-Exp-Ophthalmol　1995　233(10):655～661〔4〕AndersonEI,etal.Therolesofgluatthionereductaseandr-glutamyltranspeptidaseincornealtransendothelialfluidtransportmediaedbyoxidizedglutathioneandglucose.ExpEyeRes　1982　35:11～19〔5〕MarcosMA,CorderoY,LM,etal.Inhibiciondelalipoperoxi-dacionretinianadurantelavitrectomia.Efectodelasoluciondeirriga-cionintraocularBSSplus.Arch-Soc-Esp-Oftalmol　2001　76(10):605～612〔6〕KitamuraK,NaoIN,MaruiwaF,etal.Effectogintraocularirri-gatingsoulutiononflickerelectroretinogramduringcataractsurgeryinhumaneye.JpnJOphthalmol　1998　42(4):275～280〔7〕AraieM,etal.Intraocularirrigatingsolutionandbarrierfunctionofretinalpigmentepothelium　1997　81:150～153〔8〕StoldtWG,etal.Differentophthalmologicsurgeryirrigationsolu-tions.Studiesofpostoperativeinflammation.Ophthalmologe　1997　94:583～586〔9〕ManzanasLL,etal.Intraocularirrigatingsolutionsandvitrectomy-relatedchanges(inprotein,lacticandascorbicacid)inrabbitvitre-ous.Ophthalmic-Res　1992　24:61～67(20028)　　　315040　　　29　010820　23。1,,4。2。10、,2001104。0.01,,9mm,,,,。18.0mmHg。,。。3。10,3mm。,10,(-),。0.6,。,,,(+)。、1。3。:、、、、,1。,,,〔1〕。、、,。,(bFGF)(HGF),〔2〕。,,。〔3〕。、、,,。〔1〕,..:　1996　3054〔2〕,..:　1999　18～22〔3〕LeeSH,TsengSCG.Amnioticmembranetransplantationforpersis-tentepithelialdefectswithulceration[J].AmJOphthalmol　1997　303～312(20034)·417·21(2003)6