生物专业细胞生物学课程试题5

生物专业细胞生物学课程试题（5）一、选择填空（每小题2分，共60分，请做在答题卡上）1．ThefirstmanthatdescribedthecellstructuresisA.RobertHook.B.vanLeeuwenhoek.C.W.Flemming.D.J.E.Pukinye.2．PhasecontrastmicroscopecanbeusedtoobserveA.Alivecell.B.Stainedcell.C.Notstainedcell.D.Alloftheabove.3．Ifyouwantedtoseparateeukaryoteribosomalsubparticlesbysize,whichofthefollowingtechniqueswouldyouuse?A.Gelelectrophoresis.B.Radiolabelling.C.Polymerasechainreaction.D.Densitygradientcentrifugation.4．Whichofthefollowingdescriptionaboutprioninnottrue?A.Prionisasortofproteinthatcausingsomeseverediseases,suchasbovinesponge-formencephalopathies(BSM,madcowdisease).B.Prioncanreplicateitselfbychangetheconformationoftheproteinswhicharesimilartoprion.C.Prionisatranscriptionregulatoryprotein.D.PrionwasdiscoveredbyPrusinerin1982.5．Ingeneral,glycoproteinsandglycolipids:A.Areontheouterleafletoftheunitmembrane,facingtheenvironmentofacell.B.Areontheinnerleafletoftheunitmembrane,facingthecytosol.C.Areequallydistributedontheinnerandoutersurfaceoftheunitmembrane.D.Occuronlyininternalmembranes.6．Whichofthefollowingisnotthefunctionofthebio-membrane?A.Signaltransduction.B.Transportation.C.Transcription.D.Compartmentalization.7．InhumanintestineglucoseareabsorbedbythewayofA.Na+poweredantiport.B.Na+poweredsymport.C.Channelproteins.D.ABCtransporter.8．TheNa+/K+ATPaseofeukaryoticcellsA.IsaP-typepump.B.IsaV-typepump.C.IsanF-typepump.D.IsanATP-bindingcassette.9．Followingorganellesareallsurroundedbydoublebio-membranesexceptA.MitochondrionB.Chloroplast.C.ER.D.Nucleus.10．Cis,medialandtransspecifydifferentcompartmentsofthe...A.Golgibody.B.Endoplasmicreticulum.C.Mitochondrion.D.Nucleus.11．ThePHvalueinlysosomeislowerthanthatincytoplasmbecauselysosomemembraneexistA.P-typeH+pump.B.F-typeH+pump.C.V-typeH+pump.D.P-typeNa+-K+pump.12．Whichofthefollowingstatementsaboutsignalsequencesisfalse?A.Signalsequencesareremovedfromproteinbysignalpeptidaseafterthesortingprocesshasbeencompleted(exceptnuclearlocalizationsequence(NLS)andsignalpatch).B.Eachsignalsequencespecifiesaparticulardestinationinthecell.C.NLSdirectproteinsintocytoplasmfromnucleus.D.Anyproteinwithapropersignalsequencewillbetransferredintotheperoxisome.13．WhichofthefollowingaboutperoxisomesistrueA.Theyareformedbybinaryfissionofexistingperoxisomes.B.TheycontaintheirownDNA.C.Theycontainoxidativeenzymes.D.BothAandC14．PSIabsorblightofwavelengthatA.680nm.B.700nmC.280nmD.BothAandB15．WhichofthefollowingisnotencodedbythemtDNA?A.Cytochromec.B.Cytochromeb.C.F0.D.Keratin.16．CyclicphotophosphorylationisaccomplishedbyA.PhotosystemI.B.PhotosystemII.C.PhotosystemIII.D.BothphotosystemsIandII.17．G-proteinlinkedreceptorsareA.Single-passtransmembraneproteins.B.Seven-passtransmembraneproteins.C.Three-passtransmembraneproteins.D.Notatransmembraneprotein.18．WhichofthefollowingisNOTasecondmessenger?A.NO.B.cGMP.C.cAMP.D.IP3.19．DyneinsaremotorproteinsthatmovefromalongA.–endto+end;microtubules.B.+endto–end;microtubules.C.–endto+end;microfilaments.D.+endto–end;microfilaments.20．MicrotubulesfunctionincellsA.Asstructuralsupports,maintainingtheshapeofthecell.B.Toformthespindleduringmitosisandmeiosis.C.Asapartofthesystemthatcausesmovementinciliaandflagella.D.Alloftheabove.21．FunctionsoftightjunctionsincludeallthefollowingexceptA.Separationofextracellularfluid.B.Sealingofbodycavities.C.Preventionofdiffusionofmembraneproteinsandlipidsbetweenapicalandbasolateralregions.D.Tightcommunicationandextrangeofsmallmoleculesbetweenneighboringcells.22．Whichofthefollowingcytoskeletonstructureslinkstodesmosomesandhemidesmosomes?A.Microtubules.B.Intermediatefilaments.C.Microfilaments.D.alloftheabove.23．CellbindingdomaininfibronectinscontainA.RGDsequences.B.KDELsequences.C.Gly-XYsequences.D.PESTsequences.24．ThecoreproteinsinnucleosomeareA.H2A,H2B,H3,H4.B.H1A,H1B,H3,H4.C.H1A,H2A,H3,H4.D.H1,H2,H3,H4.25．Eukaryoticchromosomescontaintwogeneraldomainswhichrelatetothedegreeofcondensation.ThesetworegionsareA.Uniforminthegeneticinformationtheycontain.B.Calledheterochromatinandeuchromatin.C.SeparatedbylargestretchesofrepetitiveDNA.D.BothAandB26．Whatisthemainfunctionofcyclinproteins?A.Theyinitiateasignaltransductioncascadethatleadstochangesinthecell’sbehavior.B.TheyregulatethecelldivisionbybindingandactivatingCDKenzymes.C.Theyarethemainproteincomponentsofthekinetochore.D.Theyblockcellcycleprogressionwhenconditionsarenotappropriateforgrowth.27．MPFconsistsofA.CDC2andcyclinDB.CDC2andcyclinEC.CDC2andcyclinBD.CDK1andcyclinC28．NecrosisA.MaybemediatedbyFASsignalpathway.B.CharacterizedbyDNAdegradedintoabout200bpfragment.C.Isageneticallycontrolledprocess.D.Occurswhencellisinjured.29．Whichofthefollowingmutationsinatumorsuppressorgenewillmostlikelynotresultincancer?A.Pointmutant.B.Deletion.C.Generearrangement.D.Alloftheabove.30．Whichofthefollowingaboutapoptosisisnottrue?A.IsaccompaniedbyrandomDNAdegradation.B.Isasortofcellularself-destructionthattakesplaceinnormaltissues.C.Ischaracterizedbynuclearfragmentationandcellularbreakdownintoapoptoticvesicles.Anddoesnotinduceinflammation.D.Differsfromnecrosisbecausenecrosisoccur