Drugs中枢神经系统药理学概论

IntroductiontothePharmacologyofCNSDrugs中枢神经系统药理学概论121.FunctionalOrganizationofCNS2.Synaptictransimitters：Transmittersandreceptors第1节中枢神经系统的细胞学基础CNSCells1.Nervecell神经元2.Synapse突触4.Neuroglia神经胶质细胞3.Neurotransmitter神经递质第2节中枢的神经递质及其受体NeurotransmittersandReceptors1.Ach：M1-5，N觉醒，awakening学习,study记忆,memory运动,movment2.γ-aminobutyricacid(GABA)GABAA-C中枢一直效应，CNSInhibition三、兴奋性氨基酸Glutamate，GluNewDrugTarget?四、去甲肾上腺素Noradrenaline抑郁症，Depression五、多巴胺DopamineD1-4精神疾病，MentalDisease六、5-羟色胺5-Hydroxytryptamine5-HT1-7心血管，CardiacBloodVessels睡眠，Sleep精神疾病，Psychosis七-八、组胺和神经肽HistamineandNP第3节中枢神经系统药理学特点CNSAgentsClassification1.Ach-R2.NA-R3.DA-R4.5-HT-R5.GABA-R6.Gly-R7.H-R8.NP-R9.CellmembraneTargetsofCNSDrugs