R语言整合分析程序包meta官方手册(meta-analysis with R)

Package‘meta’November19,2014TitleMeta-AnalysiswithRVersion4.0-1DependsR(=2.9.1)ImportsgridSuggestsmetaforDate2014-11-19DescriptionUser-friendlygeneralpackageprovidingstandardmethodsformeta-analysis:-fixedeffectandrandomeffectsmeta-analysis;-severalplots(forest,funnel,Galbraith/radial,L'Abbe,Baujat,bubble);-statisticaltestsandtrim-and-fillmethodtoevaluatebiasinmeta-analysis;-importdatafromRevMan5;-predictioninterval,Hartung-KnappandPaule-Mandelmethodforrandomeffectsmodel;-cumulativemeta-analysisandleave-one-outmeta-analysis;-meta-regression(ifRpackagemetaforisinstalled).LicenseGPL(=2)EncodingUTF-8AuthorGuidoSchwarzer[cre,aut][e-mail]ositoryCRANDate/Publication2014-11-1919:58:1812amlodipineRtopicsdocumented:amlodipine.........................................2as.data.frame.meta.....................................4baujat............................................5bubble............................................7ci..............................................10cisapride...........................................11Fleiss93...........................................12Fleiss93cont.........................................13forest............................................14funnel............................................25labbe.............................................29metabias...........................................32metabin...........................................36metacont...........................................44metacor...........................................50metacr............................................56metacum...........................................59metagen...........................................61metainc...........................................67metainf...........................................75metaprop..........................................77metareg...........................................86Olkin95...........................................89print.meta..........................................90print.rm5..........................................94read.mtv...........................................96read.rm5...........................................98settings.meta........................................101smoking...........................................103trimfill............................................104update.meta.........................................108Index113amlodipineAmlodipineforWorkCapacityDescriptionMeta-analysisontheeffectofamlodipineonworkcapacity.Thismeta-analysisisusedasadataexampleinHartungandKnapp(2001).Usagedata(amlodipine)amlodipine3FormatAdataframewiththefollowingcolumns:studyStudylabeln.amloNumberofobservationsinamlodipinegroupmean.amloEstimatedmeaninamlodipinegroupvar.amloVarianceinamlodipinegroupn.placNumberofobservationsinplacebogroupmean.placEstimatedmeaninplacebogroupvar.placVarianceinplacebogroupSourceHartungJ&KnappG(2001),Ontestsoftheoveralltreatmenteffectinmeta-analysiswithnormallydistributedresponses.StatisticsinMedicine,20,1771–82.doi:10.1002/sim.791.SeeAlsometacontExamplesdata(amlodipine)#m-metacont(n.amlo,mean.amlo,sqrt(var.amlo),n.plac,mean.plac,sqrt(var.plac),data=amlodipine,studlab=study)m.hakn-metacont(n.amlo,mean.amlo,sqrt(var.amlo),n.plac,mean.plac,sqrt(var.plac),data=amlodipine,studlab=study,hakn=TRUE)#Resultsformeandifference-seeTableIIIinHartungandKnapp(2001)#res.md-rbind(data.frame(summary(m)$fixed)[c(TE,lower,upper)],data.frame(summary(m)$random)[c(TE,lower,upper)],data.frame(summary(m.hakn)$random)[c(TE,lower,upper)])#res.md-round(res.md,5)#row.names(res.md)-c(FE,RE,RE(HaKn))names(res.md)-c(Absolutedifference,CIlower,CIupper)#res.md4as.data.frame.metaas.data.frame.metaAdditionalfunctionsforobjectsofclassmetaDescriptionTheas.data.framemethodreturnsadataframecontaininginformationonindividualstudies,e.g.,estimatedtreatmenteffectanditsstandarderror.Usage##S3methodforclass'meta'as.data.frame(x,row.names=NULL,optional=FALSE,...)ArgumentsxAnobjectofclassmeta.row.namesNULLoracharactervectorgivingtherownamesforthedataframe.optionallogical.IfTRUE,settingrownamesandconvertingcolumnnames(tosyntacticnames)isoptional....otherargumentsValueAdataframeisreturnedbythefunctionas.data.frame.Author(s)[e-mail],metacont,metagen,forest.metaExamplesdata(Fleiss93cont)##Generateadditionalvariablewithgroupinginformation#Fleiss93cont$group-c(1,2,1,1,2)##Dometa-analysiswithoutgroupinginformation#meta1-metacont(n.e,mean.e,sd.e,n.c,mean.c,sd.c,study,data=Fleiss93cont,sm=SMD)##Updatemeta-analysisobjectanddosubgroupanalysesbaujat5#summary(update(meta1,byvar=group))##Sameresultusingmetacontfunctiondirectly#meta2-metacont(n.e,mean.e,sd.e,n.c,mean.c,sd.c,study,data=Fleiss93cont,sm=SMD,byvar=group)summary(meta2)##Compareprintoutofthefollowingtwocommands#as.data.frame(meta1)meta1$databaujatBaujatplottoexploreheterogeneityinmeta-analysisDescriptionDrawaBaujatplottoexploreheterogeneityinmeta-analysis.Usagebaujat(x,...)##S3methodforclass'