精准医疗-人工智能

PrecisionMedicinewithArtificialintelligenceSchoolofcomputerscienceandTechnology1703110270王榕ExamplePrecisionmedicineWhat’sthePrecisionMedicine?Precisionmedicineisanemergingapproachfordiseasetreatmentandpreventionthattakesintoaccountindividualvariabilityingenes,environmentandlifestyleforeachperson.----NationalInstitutesofHealthPhysicianshavehadtorelyontheirexperience,judgement,andproblem-solvingskillswhileusingrudimentarytoolsandlimitedresources.Inthepast:Howhasprecisionmedicinedeveloped?GenomicsBiotechnologyWearablesensorsArtificialintelligence(AI)ThedawnofpracticingmedicineDigitalhealthCheapgenomesequencing,advancedbiotechnology,healthsensorspatientsuseathome,andthecollectionofinformationaboutpatients’journeyinhealthcarewithhand-helddeviceshaveallbeenproducingavastamountofdata.Withthesmartphoneandhealthtrackerrevolutionsunderthenameofdigitalhealth,ithasbecomeimpossibleforaphysiciantoanalyzeallthosedataorsimplytobeup-to-date.ThereisnoprecisionmedicinewithoutAIThisapproachallowsdoctorsandresearcherstopredictmoreaccuratelywhichtreatmentandpreventionstrategiesforaparticulardiseasewillworkinwhichgroupsofpeople.precisionmedicineItrequires:significantcomputingpower(supercomputers);algorithmsthatcanlearnbythemselvesatanunprecedentedrate(deeplearning);Generally,anapproachthatusesthecognitivecapabilitiesofphysiciansonanewscale(AI).AIisdividedbroadlyintothreestages:Artificialnarrowintelligence(ANI)ArtificialgeneralintelligenceArtificialsuperintelligenceANIisthemostlikelytoappearinthenextdecade,whichcouldanalyzedatasets,drawconclusions,findnewcorrelations,andsupportphysicians’job.Therearecompaniesthathavedemonstratedhowsupercomputers,deeplearning,andANIcouldsupportprecisionmedicine(Table1).CompanyMainareaofresearchVerilyWearablesensorsIBMWatsonMiningmedicalrecordsCareskoreQualityofcareZephyrHealthIdentifyingtherapies3ScanRadiologyEnliticRadiologyArterysRadiologyAtomwiseDrugdevelopmentDeepGenomicsGenomicsTable1.Alistofcompaniesusingaformofartificialintelligencetoimprovehealthcareand/ormedicine.IBMWatsonIBMWatsonhealthlauncheditsspecialprogramforoncologiststoprovideclinicianswithevidence-basedtreatmentoptions.IBMlaunchedanotherprogramcalledMedicalSieve.Itaimstobuildthenext-generation‘cognitiveassistant’withanalytical,reasoningcapabilitiesandarangeofclinicalknowledge.MedicalSieveisqualifiedtoassistinclinicaldecision-makinginradiologyandcardiology.The‘cognitivehealthassistant’isabletoanalyzeradiologyimagestospotanddetectproblemsfasterandmorereliably.Google'sDeepMindtouseAIindiagnosingeyediseaseAscanofahumaneyeGoogleplanstominethedataofmedicalrecordsinordertoprovidebetterandfasterhealthservices.TheMenloPark,Calif.-based(加州门洛帕克)companyhassignedadealwithaBritisheyehospital(MoorfieldsEyeHospitalNHSFoundationTrust)touseartificialintelligencetolearnfromthemedicalrecordsof1.6millionpatientsinLondonhospitals.Thegoalistoteachacomputerprogramtorecognizethesignsoftwocommontypesofeyedisease,diabeticretinopathyandage-relatedmaculardegeneration.AlibabaETMedicalBrainETmedicalbrainisalicloud'sartificialintelligencesolutionplatformformedicalfield.Withabundantknowledgeandexperienceinmedicalhealthbrain,ETwillhaveanumberofmedicalability,andinpatientswithvirtualassistant,biotechnology,medicalimaging,drugmining,hospitalmanagement,healthmanagement,wearabledevicessuchasmedicine,thedoctorassistantrole.BrainCore-医疗数据中台阿里云-医疗数据中台医疗影像智能•CT辅助标注肺部病变-阿里巴巴iDST•面部皮肤检测分析-宜远智能医学语音识别•医疗语音识别-阿里巴巴iDST临床数据智能•CDSS-惠每医疗BrainAbility阿里云ET医疗脑混合云解决方案Prospectsforbroaderapplicationraisedbyrecentadvancesinbasicresearch,technologydevelopment,genomics,proteomics,metabolomics,EHRs,BigData,mHealth,etc.FutureProspects