板蓝根研究进展(1)

:1.34km2,0.134km2,0.004km2,0.00067km2,5,;4,,,;,;,2.52.22.2.1,,2.2.2,,,,,,,,,,,,,2.2.3,(),,,,,,,,,,2.2.4,,,,崔树玉,薛　原,杨建莉,郝　坚(,710075):R282.71:A:02532670(2001)07067002,,,IsatisindigoticaFort,,,,11.1[14]:(indigotin,indigo)(inderubin)(indican)(isatin)(adenosine)1-(glucobrassicin)(3-indolylmethylglucosinolate)(isatanA)(isatanB)(tryptanthrin)1--2--3-(1-thiocyano-2-hydroxy-3-butenen)(epigoitrin)2,4(1H,3H)[2,4(1H,3H)quina-zoliedione]4(3H)-1.2:--1.3:-1.4:(linolenicacid)(erueicacid)22.1[5]:,,,,,2.284g2.2[612]2.2.1:,12d,,,100%60%70%2.2.2:(HFRSV)(HSV-2)Vero-6BGM,,670ChineseTraditionalandHerbalDrugs2001327:2001-03-01:(1962-),,,,Tel:[phone]:()HBsAg,2.2.4(HCMV):(HCMV),MTT,1200,HCMV,DNAYamada,,7ku,17.5%,21.5%,28.6%2.3[13,14]:D111B4,,,,400U/mL1U/mL10kGy2.4[15]:(IIP)50mg/kg,:,(HC),,HCIIP(CDNB),(NK)IIPA(conA),IIPIIP2.5[16]2.5.1Friead3CL-:3CL-850%0.2mL,1,7d,,3CL-8,2.5.2(CML):-,,,DNAI74%5-(5-N)1.56(8/8),4/82.6[17]:Hamaue(MAO),(NE)5-(5-HT),2h(Ach)(DA)ParkinsonsDA:;;;ANP3,,,,,:[1].[J].,1983,14(6):24.[2],,,.[J].,1998,8(2):132-134.[3]SeipertK,UngerW.InsecticidalandfungicidalcompoundsfromIsatistinctoria[J].ZNaturforschCBiosci,1994,49(1-2):44-48.[4],,,.[J].,1994,29(2):128-131.[5],,,.27[J].,1991,10(3):40.[6],,,.50HBsAg[J].,1992,9(5):208.[7],[J].,1995,26(5):297-299.[8],,,.[J].,2000,21(3):204.[9],,,.[J].,1999,30(9):650-651.[10],,,.MTT[J].,2000,24(2):137.[11]YamadaHarudi.Antiviralcompositionscontainingnewgly-coproteinfromIsatistinctoria[P].JP:1160,599[9960,599],1999-03-02.[12]YamadaHaruki.NovelpalysaccharidefromIsatistinctoriaasanti-viralantibodyformationpromoterandvaccinoadvuvant[P].JP:11236,402[99236,402]1999-08-31.[13],.[J].,1994,19(2):88.[14].[J].,1993,24(8):413.[15],,,.[J].,1991,11(6):357-359.[16].50%Friend3CL-8[J].,1994,25(8):417.[17]HamaueNaoya.PharmacologicalroleofIsatin,anEndoge-nousMAOinhibitor[J].YakugaduZasshi,2000,120(4):352.ChineseTraditionalandHerbalDrugs20013271