多巴胺、多巴酚丁胺、硝酸甘油联合治疗顽固性心力衰竭42例临床观察

2008121423154ContemporaryMedicine,Dec.2008,Vol.14No.23IssueNo.154Medication&Clinial200022008342(36)11.178EF20%40%NYHA3642,,ACEI3,[1]78422616793263.51861653,182236783464.615312721820p0.05)1.2ACEI:10%500ml+10%10ml+10,()+15g/kg.min210g/kg.min2100g/kg.min351.3I42[]78ACEI,(42)(36),()105281090.5%51555.6%p0.05)[]I24833.1[2]1[0.52g/kg.min][210g/kg.min]1[1020g/kg.min]a,1[3]90.5%3.2CCU[]N()()(%)()4228104(9.5%)42(90.5%)3651516(44.4%)36(55.6%)18p0.05)3()14980mmHg4449002008121423154ContemporaryMedicine,Dec.2008,Vol.14No.23IssueNo.1545Medication&Clinial[]1405070Gy762316130405864+B12242421%37%P0.05(14.472.98)(23.684.26)P0.01[][Abstract]ObjectiveToobservethefunctionofgromwellrootoilcombinedwithhyperthermiatreatmentforpreventingandcuringskinharmfromradiotherapy.MethodsFrom140malignanttumorpatients,receivedtraditionalradiotherapydoseseparationofdifferenthistologicalposition,weredividedintotworandomgroups.Thetotalradiationtreatmentdoseofthetwogroupsarrived50~70Gy,andthetreatmentbeganassoonasIdegreeskininjuredappearance.76patientsbelongedtoTreatmentgroup,merelypaintedtheirskinofradiotherapyfieldswithgromwelloiltwoorthreetimeseverydayafterradiationtreatmentatearlyperiod,withtheaccumulativedoseincreasing,16patientsII~IIIdegreesskinharmemerged,andthen,besidesthepaintingofgromwelloil,meanwhiletheyalsoreceivedhyperthermiatreatment1timeseverytwodays,30~40minutesonetime,5~8timesfortotal.64patientsincludedinComparisongroup,appliedtheirskinofradiotherapyfieldswithdexamethasoneinjectionaddedvitaminB12injection,2~4timeseveryday,untiltotheterminationofradiationtreatment.Inthisgroup,24patientsII~IIIdegreesskinharmwasobserved.ResultsAccordingtotheappearancerateofII~IIIdegreesskinharm,theTreatmentgroupandtheComparisongroupoccupied21%and37%respectively(P0.01).Recovertime,theaveragerecoverdaysbetweentheTreatmentgroupandtheComparisongroupwere(14.472.98)and(23.684.26)(P0.01)respectively.ConclusionGromwellRootoilcombinedwithhyperthermiatreatmentwouldcutdowntheacuteharmdegreesofskinwiththeradiationtreatment,decreasethetimeofrecoveryofskin,andwerehelpfulforcompletingthewholeradiationtreatment.[KeyWords]GromwellRootoil;hyperthermiatreatment;theacuteskinharmofradiotherapy11.114070,,,,,3175,53,48,92,42,14,32,268,7,41.265500024h24h[5][1]....,2002.192[2]....,2002.194[3]....,19971363-1364[4]Braunwald().....5.636[5]B()5,5102000.4-44raunwald......2000.48