粉末活性炭脱色液的微孔过滤

宋显洪(,200040)　(PA)PGH,。、、。　　　　　(1g800～2000m2/g),、、,(),。,“”,。,,,。、。1　:1):1～2μm,15μm,3～7μm。2):100°C,85～90°C。3),,,;,,。,:1),,,“”。()400(46μm),1μm。2),,,,,,,,。2　,,:1)1μm,。2)、。100°C。3),,。,;,,。4),,。,PA,,:、(≤110°C)——PAPGH。,PA,,,,。·276·　ChineseJournalofPharmaceuticals1999,30(6):、,,,,,,,。3　3.1　PAPA(5～30μm),、、、。,:ds=dm_Δs1A-BlnuX(1):ds—(μm)dm—(μm)_—(N·s/m2)u—()(m/h)X—(%)ΔS—(mm)A,B—,,。　　,:A=0.302,B=0.127。　　(1),dsPAdm。ΔS=9mm。:ds=1μm,_=0.002Ns/m2,u=0.8m/h,X=0.40A=0.302,B=0.127　　(1)dm=14.3μm。3.2　。F:F=VTCR2m+1.962ΔPTCt_-Rm(2):V—(m3)C—()t—(s)_—(N·s/m2)ΔP—(N/m2)Rm—(1/m)T—(1/m2)(2)C,V、t,Rm,ΔPT(),。ΔP:0.20mPa,1.96×105N/m2。T:(1～9)×1014　1/m2:。:V=4m3,t=3600s,ΔP=1.96×105N/m2;　T=5×1014,_=1.5×10-3N·s/m2,C=0.02,Rm=4×10111/m2,(2)F=14.8m2。3PGH-5,5m2。4　1978,。。3,PGH,、,。。4.1　酸性中和液活性炭过滤:　:80°C;:0.15MPa;:6kg/m3();:0.86×10-3N·s/m2;:0.6m3/(m2·h)。一次脱色液活性炭过滤:　:80°C;:0.15MPa;:6kg/m3();:1.71×10-3N·s/m2;:0.3m3/m2·h。·277·　ChineseJournalofPharmaceuticals1999,30(6)二次脱色液活性炭过滤:　:80°C;:0.2×106N/m2;:6kg/m3();:2.4×10-3N·s/m2;:0.25m3/(m2·h)。4.2　:85°C;:(0.15～0.2)×106N/m2;:6kg/m3();:2.0×10-3N·s/m2;:0.35～0.4m3/(m2·h)。4.3　:50°C;:(0.15～0.20)×106N/m2;:12kg/m3();:4×10-3N·s/m2;:0.18m3/(m2·h)。1　.,1984:(4)∶32　.,1989;(3)∶213　.,1994:276-282MICROPOROUSFILTRATIONOFPOWDERACTIVECARBONSONGXian-Hong(ShanghaiInstituteofPharmaceuticalIndustry,Shanghai200040)ABSTRACT　Usingtherigidsinteredpipesmadebymicroporouspolymerasmedia,themicroporousfiltermodelPGHwasdesignedandmanufacturedtosolvethedifficultfiltrationproblemofpowderactivecarbon.Ithasbeenappliedindecolorizationofglucose,caffeineandaminoacidssolutions.KeyWords　powderactivecarbon,precisemicroporousfiltration,cake[1998119]封面:;封二:;彩插1:();彩插2:(),;插1:;插2、3:;插4:;彩插3:;彩插4、5:;彩插6:;插5:;插6:;插7:;插8:、;288页:;插9:;插10:;彩插7:;彩插8:;封三:;封底:、。·278·　ChineseJournalofPharmaceuticals1999,30(6)