年产30万帖烧伤敷料车间工艺设计

本科毕业设计（论文）题目年产30万贴烧伤敷料车间工艺设计姓名刘苗专业高分子材料与工程学号20132073指导教师高光辉长春工业大学化学工程学院2017年3月27日I摘要传统烧伤敷料吸液量不够大,需要厚厚包扎并经常更换，敷料在吸液后易干燥,并与伤口发生粘连而造成二次创伤,又不便使用等缺点,所以逐渐被其它敷料代替。水凝胶是一种含有大量水分的亲水性的网状高分子溶胀体,具有良好的吸水性，表面光滑,生物相容性好,所以在生物医学工程领域得到了广泛的研究和应用。水凝胶敷料能与不平整的创面紧密帖合但不粘连,减少细菌滋生的机会。本设计对水凝胶烧伤敷料的生产进行了工艺设计。设计内容主要包括：配方的选取、物料衡算、车间工艺设计、生产设备的选取、生产车间的设计等。并对涉及的聚合方法进行了介绍，对公用系统进行了简单说明。除此之外，在本设计中绘制了工艺流程图、车间布置图以及主要设备图。关键词：水凝胶烧伤敷料合成高分子合成敷料理想敷料IIAbstractTraditionalburnsdressingisnotlargeenough,needthickdressingandfrequentreplacement,dressingintheliquidaftertheeasytodry,andthewoundadhesioncausedbysecondarytrauma,andinconveniencetouseandothershortcomings,sograduallyreplacedbyotherdressings.Hydrogelisahydrophilichigh-molecularpolymerswellingbodycontainingalotofwater.Ithasgoodwaterabsorption,smoothsurfaceandgoodbiocompatibility.Therefore,ithasbeenwidelystudiedandappliedinbiomedicalengineering.Hydrogeldressingscanbecloselytiedwithunevencreaturesbutnotsticky,reducingthechanceofbacterialgrowth.Thisdesignhasbeencraftedfortheproductionofhydrogelburndressings.Thedesigncontentincludes:theselectionofrecipe,materialaccounting,workshopprocessdesign,productionequipmentselection,productionworkshopdesign.Theintroductionofthepolymerizationmethodisintroduced,andthecommonsystemisbrieflydescribed.Inadditiontothisdesigninthedesignoftheprocessflowchart,thelayoutoftheworkshopandthemainequipmentmap.Keywords:Hydrogels；Burndressings；Syntheticpolymer；Syntheticdressings；Idealdressing.1目录第一章绪论-----------------------------------------------------------------------------------------------------------------------41.1水凝胶烧伤敷料的简要概述---------------------------------------------------------------------------------------41.2水凝胶烧伤敷料的发展现状---------------------------------------------------------------------------------------41.3几种常用敷料的对比-------------------------------------------------------------------------------------------------51.3.1传统敷料和生物敷料------------------------------------------------------------------------------------------51.3.2合成敷料-----------------------------------------------------------------------------------------------------------51.3.3水凝胶敷料--------------------------------------------------------------------------------------------------------61.4理想敷料应该具备的功能------------------------------------------------------------------------------------------71.5作为创伤敷料设计水凝胶的原则-------------------------------------------------------------------------------71.6水凝胶创伤敷料课题研究的意义-------------------------------------------------------------------------------7第二章配方设计----------------------------------------------------------------------------------------------------------------82.1主要原料-----------------------------------------------------------------------------------------------------------------82.1.1对苯二酚-----------------------------------------------------------------------------------------------------------82.1.2氰基丙烯酸丁酯------------------------------------------------------------------------------------------------92.1.3丙二醇--------------------------------------------------------------------------------------------------------------92.1.4壳聚糖------------------------------------------------------------------------------------------------------------102.1.5羧甲基纤维素钠-----------------------------------------------------------------------------------------------122.1.6明胶----------------------------------------------------------------------------------------------------------------142.2聚合方法---------------------------------------------------------------------------------------------------------------152.2.1悬浮聚合---------------------------------------------------------------------------------------------------------1622.2.2悬浮聚合的组成-----------------------------------------------------------------------------------------------162.2.3悬浮聚合工艺--------------------------------------------------------------------------------------------------162.2.4悬浮聚合的优缺点--------------------------------------------------------------------------------------------172.3配方的设计-----------------------------------------------------------------------------------------------------------17第三章物料衡算--------------------------------------------------------------------------------------------------------------183.1概述---------------------------------------------------------------------------------------------------------------------183.2物料衡算基准--------------------------------------------------------------------------------------------------------183.3总需料量的计算-----------------------------------------------------------------------------------------------------183.4物料衡算---------------------------------------------------------------------------------------------------------------19第四章设备选型-------------------------------------------------------------------------------------------------------------214.1设备的选择原则-----------------------------------------------------------------------------------------------------214.1.1选型的原则---------------------------------