多级厌氧法处理螺旋霉素工业发酵菌渣效果的研究朱培

82Vol．8No．220142ChineseJournalofEnvironmentalEngineeringFeb．20141222213*1.2002372.2000403.200040。44L411L。121d31.27、1.822.73kgCOD/m3·d。。2。2.73kgCOD/m3·d45%1。。80d2.73kgCOD/m3·d97%COD90%。X787A1673-9108201402-0703-06PerformanceoffourstagesanaerobicreactorsystemintreatmentofspiramycinmanufacturingbiowasteZhuPei12ZhangJianbin2LiJian2ShaoLei2ChuJu1ChenDaijie31.StateKeyLaboratoryofBioreactorEngineeringEastChinaUniversityofScience＆TechnologyShanghai200237China2.StateKeyLaboratoryofNewDrug＆PharmaceuticalProcessShanghaiInstituteofPharmaceuticalIndustryShanghai200040China3.ChinaStateInstituteofPharmaceuticalIndustryShanghai200040ChinaAbstractSpiramycinmanufacturingbiowastewastreatedbyafourstagesanaerobicreactorsystem．Thevolumeofthesystemwas44Lbeingdividedintofour11Lstageseachofthestagewasconnectedbyseries．ThesystemwasoperatedwiththreestepsintheorganicloadingrateOLＲof1.271.82and2.73kgCOD/m3·d．Theprocessperformanceofthesystemwascharacterisedintermsofitsbiogasvolumeandspiramycinreduction．Thesystemcouldreachitsstablestateinbiogasproductionaftertwomonthoperation．About45per-centofallbiogaswasproducedfromthestage1attheOLＲof2.78kgCOD/m3·d．Thoughspiramycinwasnoteliminatedrapidlyatthebeginningafter80daysanaverageof97%spiramycinand90%CODreductionwereachievedattheOLＲof2.78kgCOD/m3·dindicatingthatthisantibioticcouldbedegradedefficientlyintheanaerobicreactorsystem．KeywordsfourstagesanaerobicreactorsystemspiramycinCODmanufacturingbiowastedegradation“”2012ZX092011012013－01－292013－02－261987～。[e-mail]*[e-mail]ycesspiramycetic-us1。2090pharmaceuticalsandpersonalcareproductsPPCPs2、3-5。。8。61%199210%1998。20027。2008《》8。。70%～80%2000/t。。、。、9-11。。anaero-bicbaffledreactor12。。。1314。COD。11.11。1#、2#、3#4#。80cm14cm20cm。10cm。6cm。。。。1Fig.1Fourstagesanaerobicreactorsystem1.2pHSartoriusPB-10。COD12000r/min10minHACHDＲ890。Waters1525。NikonE100。1.32UASB。。1.41.4.130L2.0%3∶724L37℃80r/min、5min2。3L。4d2.0%2L411L。1.4.2。1#40724#。2。121d31。112.0%COD14000mg/LCOD6500mg/L4LOLＲ1.27kgCOD/m3·d。232。22.0%4LCOD20000mg/LCOD10000mg/L。34.0%COD40000mg/LCOD18000mg/L3L。pH10dCOD。1Table1SummaryofreactoroperatingconditionsofthefourstagesanaerobicreactorsystemdOLＲkgCOD/m3·dCODmg/L11～581.2714000259～921.8220000393～1212.73400001.4.32h。Welchrom-C185μm4.6×250mm232nm35℃A50mmol/LBA∶B=63∶371mL/min。。BacillussubtilisLB37℃。22.1pHpH。1#pH7.5～8.04#pH7.72pH。113～14L/d“”1#2#3#。1#2#。。3449。21#＞2#＞3#＞4#。2、pHFig.2BiogasproductionofeachstagetotalbiogasproductionandpHoftheeffluentatstage4atdifferentOLＲ22。212120L/d50%2143%。3250%1.82kgCOD/m3·d2.73kgCOD/m3·d。3225%25L/d。3L4.0%。232。225078。1.82kgCOD/m3·d2.73kgCOD/m3·d1#11L/d。231#55%45%。1Chelliapan15UASＲ。2.2COD122%2。25、35、45278、88。32COD6500mg/L10000mg/LCOD1600mg/L1200mg/L。COD75%88%。2COD11。COD。325、35、45、7888CODFig.3SolubleCODof25th35th45th78thand88thdayinfluentsandeffluents3102112COD。64COD18671±1479、10303±772、7693±973、3884±12721868±402mg/LCOD90%。50%2.73kgCOD/m3·dCOD90%。1#50%1#45%。2.32.3.1。242%4。。4abFig.4Microscopicalmorphologicalcharactersofinfluentandeffluentofthefourstagesanaerobicreactorsystem2.3.21。2SPMⅠ、Ⅱ、Ⅲ30.30、2.702.17mg/g5.2mg/g。68d5SPMⅠSPMⅡ0.10mg/gSPMⅢ1.426072mg/g。10d78d30.2mg/g。10d88d0.2mg/g。2SPM95%Castiglioni166SPM0%～11%SPM。568、7888SPMFig.5ＲesidualSPMof68th78thand88thdayeffluents6102112SPMCODFig.6ＲesidualSPMandsolubleCODof102thand112thdayforeachstage3102112。6SPM2.99±0.05mg/g1#2#3#4#0.91±0.250.39±0.120.19±0.020.08±0.01mg/g97.3%。1#70%。7。321SPM97%。7102112Fig.7Bioactivityof102thand112thdaysamplesforeachstage312、COD。2。1.82kgCOD/m3·d20L/d12.73kgCOD/m3·d25L/d25%COD。3COD。1COD75%。23COD90%。4。88d2.73kgCOD/m3·d97%。5。。1．．7078198222113-16YuQiwei．Anewkindofstreptomycetewhichcanproducespiramycin．ActaMicrobiologicaSinica198222113-16inChinese2DaughtonC．G．TernesT．A．Pharmaceuticalsandper-sonalcareproductsintheenvironmentAgentsofsubtlechangeEnviron．HealthPerspect．19991076907-9383MartaC．FranciscoO．JuanM．L．etal．Behaviorofpharmaceuticalscosmeticsandhormonesinasewagetreatmentplant．WaterＲes．200438122918-29264SnyderS．A．WesterhoffP．YoonY．etal．Pharma-ceuticalspersonalcareproductsandendocrinedisruptorsinwaterImplicationsforthewaterindustry．Environ．Eng．Sci．2003205449-4695TernesT．A．MeisenheimerM．MsdowellD．Ｒemovalofpharmaceuticalsduringdrinkingwatertreatment．Environ．Sci．＆Technol．200236173855-38636AndersonA．D．NelsonJ．M．ＲossiterS．PublichealthconsequencesofuseofantimicrobialagentsinfoodanimalsintheUnitedStates．Microb．Drug．Ｒesist．200394373-3797176．200281．20089AlvarezJ．A．OteroLLemaJ．M．etal．Theeffectandfateofantibioticsduringtheanaerobicdigestionofpigmanure．BioresourceTechnol．2010101228581-858610OsmanA．A．Degradationandmetabolizationofchlortet-racyclineduringtheanaerobicdigestionofmanurefrommedicatedcalves．J．Hazard．Mater．20081582-3485-49011FerndezanJ．PerezM．ＲomeroL．I．Effectofsub-strateconcentrationondrymesophilicanaerobicdigestionoforganicfractionofmunicipalsolidwasteOFMSW．BioresourceTechnol．200899146075-608012BarberW．P．StuckeyD．C．TheuseoftheanaerobicbaffledreactorABＲforwastewatertreatmentAre-view．WaterＲes．19993371559-157813AlvesM．PereiraA．MotaM．