高级微生物

AdvancedMicrobiologyJiandongJiangDepartmentofMicrobiology,CollegeofLifeSciences,NanjingAgriculturalUniversity09/17/2014Briefintroductionofthiscourse•AdvancedMicrobiology,isanobligatorycourseforgraduatestudentswhomajorinmicrobiology.•Thiscoursewillbeconductedinfallsemesterfor1styeargraduatestudents.•Thecoursewillbegivenbyseveralprofessors/lecturers,withemphasisontheadvancementsinmicrobiology,andworldfamousprofessorswillalsobeinvitedtogivelectures.Classhour:48h(from3thweekto20thweek,3h/week)Credit:3Time:everyWednesday,10th-12thclasses(excepttheholidays)Placeforclass:Teachingbuild.B105Howtogetyourscores:Ordinaryperformance(includingyourattendancerate):30%Finalpaper:70%Attheendofthecourse,youarerequiredtosubmitareviewpaperrelatedwiththeresearchadvancementinthefieldofmicrobiology(inEnglish)Calendarofthecourse项目Time内容摘要Content讲课任课教师Teacher第3周9月17日(17thSep.)“AnintroductiontotheAdvancedMicrobiology”and“Microbialdehalogenationofhalogenatedaromatics”3蒋建东JiandongJiang第4周自9月24日(24thSep.)SpeciesandevolutionoftheEpichloae3纪燕玲YanlingJiNationalholiday第6周10月8日(8thOct)Biologyofgrass-endophytesymbiosis3纪燕玲YanlingJi第7周10月15日(15thOct)Quorumsensing:Conversationbetweenbacteria3王卉HuiWang第8周10月22日(22thOct)BacterialstressresponsesI3徐冬青DongqingXu第9周10月29日(29thOct)BacterialstressresponsesII3徐冬青DongqingXu第10周11月5日(5thNov)Yeastgeneticsandmolecularbiology3梁永恒YonghengLiang第11周11月12日(12thNov)TRAPPcomplexesandvesicletrafficking3梁永恒YonghengLiang第12周11月19日(19thNov)FromDNAtoprotein3-DimensionalstructureI3王伟武WeiwuWang第13周11月26日(26thNov)FromDNAtoprotein3-DimensionalstructureII3王伟武WeiwuWang第14周12月3日(3thDec)Theadvancementsinthemethodsofmicrobiology3洪青QingHong第15周12月10日(10thDec)BiofilminBacteria3钟镇涛ZhengtaoZhong第16周12月17日(17thDec)Microbialdegradationofnitrobenzenes3蒋建东JimC.Spain第17周12月24日(24thDec)Anovelhydrolaserecentlyfound3蒋建东JimC.Spain第18周12月31日(31thDec)BacteriaSecretionSystem3钟镇涛ZhengtaoZhong第19周1月7日(7thJan)BacteriainteractwithHost3钟镇涛ZhengtaoZhongTeachinggroupHongQingProfessorPhDofNJAUVisitingscholarofMichiganStateUniversityLiangYonghengProfessorPhDofNationalUniversityofSingaporePostdoctorofUICJiYanlingLecturerMDofNJAUTrainingforbilingualteachinginUICJiangJiandongProfessorPhDofNJAUVisitingscholarofCornellUniversityWangWeiwuProfessorPhDofSIPS(CAS)PostdoctorofTheUniversityofTexasWangHuiAssociateprofessorPhDofNJAUVisitingscholarofUniversityofPennsylvania•Dong-QingXu•AssociatedProfessor•ResearchInterests:Microbialphysiologyandmicrobialenzymes•e-mail:[e-mail]•Office:C7019PlantEndophytesJiYanlingLecturerMDofNJAUTrainingforbilingualteachinginUniversityofIllinoisatChicagoEndophytebenefitstoagronomyincreasingplantresistance•drought•Cold-stress•diseaseFestucapratensissheath(NaturalSEM)1.LifeCyclesofepichloaeendophytes2.Speciesandevolutionofendophytes3.HostCompatibility4.Biologyofgrass-endophytesymbiosisCollegeofLifeSciencesMicrobiologyHuiWang•Area:QuorumsensingregulationinbacteriaanditseffectsonbacterialphysiologicalfunctionsQuorumSensingConversationbetweenbacteriaQuorumSensingisoneofthetophotfields-5000papersafteritwascoinedin1994.SinglecellLowautoinducerTargetgeneoffGrowingaggregateIncreasingautoinducerTargetgeneoffBacterialquorumAutoinducercombinedtoregulatorTargetgeneonBioluminescenceVirulenceQuorum sensing controls multiple functionsSensingQuorum Sensingantibiotic productionBiofilmNodulationConjugationfruitingbodydevelopment…………Outline•Definitionandbackground•Quorumsensingingramnegativebacteria•QuorumquenchingDong-QingXuAssociatedProfessorResearchInterests:Microbialphysiologyandmicrobialenzymese-mail:[e-mail]:C7019BacterialstressresponsesHowdobacteriaadapttothechangesoftheenvironment?•Strategies•Regulationlevels•ExamplesDr.YonghengLiangCollegeofLifeSciencesNanjingAgriculturalUniversityNanjing210095Tel/Fax:[phone]Researchinteresting:ProteintraffickingineukaryoticcellsHomepage:=25&m=3&i=47•Yeastgeneticsandmolecularbiology•TRAPPcomplexesandvesicletraffickingYeastasoneofthemodelorganisms,hascontributedalottothestudiesofgenetics,molecularandcellularbiology.YeastLelandH.HartwellR.Timothy(Tim)HuntSirPaulM.Nurse2001NobelPrizeforPhysiologyandMedicineAfewstudiesfromyeasthavereceivedsignificantattention.Someofthemhavereceivedthemostprestigiousprize,theNobelPrize.Theyidentifiedcelldivisioncyclegene,CDC,andcyclinfrombuddingyeastandfissionyeastwithtemperaturesensitivemutants.2013NobelPrizeinPhysiologyandMedicinefortheirdiscoveriesofmachineryregulatingvesicletrafficThelatestNobelPrizeregardingyeastisthe2013NobelPrizeinPhysiologyandMedicineforthediscoveriesofmachineryregulatingvesicletraffic.Randysheckmanisayeastbiologist.NextNobelPrize?WhatwillbethenexttopicfortheNobelPrizeregardingyeast?Mostlikelyitwillbeautophagy,whichwasheavilystudiedwithyeast,especiallyfortheregulatorymechanism.IthasalreadybeenpredictedtobeawardedtheNobelPrizedbySCIENCEWATCHofThomsonReutersbasedontheimpactofAutophagyonhumanbeings.Prof.Wei-WuWangResearchInterests:ProteinstructureandfunctionE-mail:@njau.edu.cnOffice:C7019FromD