新型杀菌剂戊唑醇的合成工艺

,,,(,471003)1,2,4,,,;1,2,4;TQ455.4A0517-6611(2007)01-00144-01SynthesisTechnologyofTebuconazole,aNewStrobilurinHUANGXin-huietal(HenanUniversityofScience&Technology,Luoyang,Henan471003)AbstractUsing1,2,4-1H-triazdeasthestartingmaterial,tebuconazolewassynthesizedbythereactionofeapoxidationoftebuconazoleandtriazolesinthepresentofsodiummethoxide.KeywordsTebuconzole;1,2,4-1H-triazole;Bactericide,,tebuconzole,1-(4-)-3-(1-H-1,2,4--1-)-4,4-3,,,,,5060,,,,,:,,,1,2,4,11.11.1.1JJ-2,SHZ-DA,HH-SIS,TG328B,DHG-9070A,FTP-90E1.1.295%,95%,,,,,,,,,1,2,4-,,1.2:(CH3)2SO4+(CH3)2S(CK3)3S+CH3SO4::22.124.6g,,,(1979-),,,,2006-07-20,NaOHNaOCH3HOCH3,,64(65),NaOCH3,NaOH()2.234.16g100ml,63.07g300ml,,,A,67.35g150ml14.58g,30min,A,6681,,,3;NaCl1,;,,,,:2-(4-)-2-2.32-(4-)-2-1,2,4-,,150,,17.9g2-(4-)-2-6.9g1,2,4-150ml150,20h,,NaCl,,31,,=11,,12.6g,23.4g:(12.6/23.4)100%=53.8%(192),JournalofAnhuiAgri.Sci.2007,35(1):144,192,,,,,,,,,,3.3,,,,;,,,,,;,,,,,,,,,,,,,,3.4,;,,,,,,;,;,,,,,,()3.5,,,,,,;,;;,,,,,,,[1].[J].,2005(21):108-113.[2].20012002[J].,2003(3):4-6.[3],.[J].,2004,14(2):54-58.[4].[J].,2005(7):22-25.[5].[M].:,2002-2005.[6].[J].,2003,19(5):14-18.[7],[M].:,2001.[8].[M].:,2002.[9].[J].,2003,35(6):441-449.[10],,.[M].:,2005.[11],.[J].,2001(12):18-12.(144)2.4,306(307.8),103(105),200.125Mpa(0.13Mpa)TLC,:2032ml/L,200g/L,0.1g/L,5010g/LpH47,,3,,150,[1]SHIGEOM.Stabilizationofhalogencontainingresincompositi:JP,200260640[P].2002-02-16.[2]ROLFD,MARKUSK,JOSEFKK,etal.HeatstabiersforPVC:EP,67-750[P].1995-10-18.[3]MUHAMMADD,HUSSNAINNK,TOUSEC.Synthesisandthermalstudyofbispyridinecobalt(II)dibenzoMethanecomplex[J].JNatSciMath,1994,34(2):71-86.[4],,,.[J].,2004(15):3-5.[5],,,.[J].,2005(6):4-7.[6].[J].,2004(4):5-6.[7],.20%[J].,2004(9):6-7.[8],.2%[J].,2005(7):7-8.[9],,,.[J].,2004(2):7-9.2912007