DL_羟基蛋氨酸钙相对于DL_蛋氨酸的生物学效价

20104615NutritionandFeedstuffs·———————————————————————————2009-03-132009-11-03200BAD12B061983-*DL-DL-MHA-CaDL-DLM。792AA116。DLMDL-MHA-Ca0.03%、0.06%、0.10%、0.15%0.21%。35d7~21d22~42d2。7~21d7~42d、/、、、、P0.05DL-MHA-CaDLM7~21d71％66％/7~42d63％、58％/、74%、60%、49%、71%72%。DL-DL-S831.5A0258-7033201015-0035-06DL-DL-1,21111*1.1000812.100044。DL-DLM99%DL-DL-MHA-Ca84%11%～12%2。、。DL-MHA-CaDLM。2090。DL-MHA-Ca。、DL-MHA-CaDLM。11.1DLM99%DL-MHA-Ca84%。1.21AANY/T33-2004-2.5mm1。1.3312001AA7792112612。35d7~21d22~42d2。、、《AA》。1.41.4.121423520104615·NutritionandFeedstuffs。。7~217~42、/。1.4.242460℃80~100s3h、、、、、、、、、、、、、%%%%[2]。1.5SASANOVADuncan′s。Littell[3]y=a+b×[1-e(c1x1+c2x2)]yaba+bc1DLMc2DL-MHA-Ca。DL-MHA-CaDLMc2/c1x1、x2DLMDL-MHA-Ca。227~21d7~42dP0.05P0.05。34DLM5DL-MHA-Ca。。1~9。DL-MHA-Ca7~21d71%R2=0.79、/66%R2=0.567~42d63%R2=0.59、/58%R2=0.52、74%R2=0.74、60%R2=0.72、49%R2=0.47、71%R2=0.4872%R2=0.76。33.12DLMDL-MHA-Ca/%/%（7~21d）/%（22~42d）/%000001DLM0.030.0300.0280.0282DLM0.060.0610.0550.0553DLM0.100.1010.0900.0884DLM0.150.1520.1520.1295DLM0.210.2120.1820.1716DL-MHA-Ca0.030.0360.0390.0317DL-MHA-Ca0.060.0710.0620.0608DL-MHA-Ca0.100.1190.1080.1029DL-MHA-Ca0.150.1790.1570.15510DL-MHA-Ca0.210.2500.2260.221DLMDL-MHA-Ca99%84%299%84%15014917~2122~42/%53.0057.20（43%）29.8824.48（46%）10.0011.003.003.60（78%）0.300.30（35.4%）1.201.40（16.5/21%）2.001.400.300.30（50%）0.100.100.200.200.020.02100100/（MJ·kg-1）12.4312.76/%20.9019.20/%0.980.91/%0.470.37/%1.251.13/%0.290.27+/%0.600.5888mg95mg100mg12.5mg0.105mg0.9mgA12500IUD34480IUK33.0mgB11.5mgB26.0mgB63.0mg14.0mgBl20.02mg0.1mgE30IU80mg1.5mg。、AOAC[1]3620104615NutritionandFeedstuffs·0616±19g1.786±0.075a1100±42d2269±47d2.115±0.079a4800±189aDLM0.030677±24ef1.658±0.015bc1123±42cd2355±69c2.063±0.083bc4854±162aDLM0.061702±18de1.635±0.087bcd1148±68abcd2374±71c2.004±0.046cd4759±217aDLM0.101744±21ab1.569±0.031def1167±50abc2470±28ab1.964±0.040def4852±70aDLM0.152760±16ab1.504±0.102f1144±95abcd2485±32ab1.933±0.071ef4803±164aDLM0.212770±21a1.563±0.050ef1203±28a2501±84a1.951±0.012ef4878±150aDL-MHA-Ca0.036657±39f1.684±0.019b1105±57d2273±110d2.097±0.070a4861±405aDL-MHA-Ca0.071701±17de1.625±0.049bcde1140±48bcd2359±51c2.019±0.038bc4762±125aDL-MHA-Ca0.119712±32cd1.603±0.041cde1142±43abcd2421±66bc1.995±0.050cde4829±98aDL-MHA-Ca0.179737±29bc1.607±0.097ecd1183±41abc2459±74ab1.990±0.053cde4892±97aDL-MHA-Ca0.250764±29ab1.559±0.036ef1191±41ab2466±68ab1.968±0.041cde4851±126a/%7~217~42/g//g/g//g/%/g/g/%/g/g02146.3±226.5f350.6±47.0g16.3±1.3f388.4±52.4f1682.0±196.9gDLM0.0302285.8±204.9de394.0±50.2ef17.2±1.6bcd402.2±62.8def1789.4±190.4efDLM0.0612326.8±258.9cd414.2±70.6de17.7±1.3bcd418.6±78.2cde1842.5±229.6bcdDLM0.1012402.5±192.4bc440.0±48.8bcd18.30±1.4b426.6±47.2bcd1901.2±141.7bcdDLM0.1522530.0±129.0a467.0±52.4ab18.5±1.8ab456.2±26.0a2027.3±109.0aDLM0.2122535.3±142.7a489.0±40.0a19.3±1.2a448.6±29.4ab2034.3±107.9aDL-MHA-Ca0.0362208.0±213.8ef369.0±59.8fg16.7±1.9ef395.0±48.2ef1737.4±173.9fgDL-MHA-Ca0.0712304.0±195.2cde390.2±49.8ef16.9±1.6def412.0±44.6cdef1817.0±161.9defDL-MHA-Ca0.1192403.0±198.9bc423.8±45.6d17.7±1.5bcd434.6±51.4abc1899.8±161.5bcdDL-MHA-Ca0.1792435.1±136.8ab438.0±32.0cd18.0±1.4bc431.8±49.4abc1926.5±119.5bcDL-MHA-Ca0.2502495.8±145.1ab454.2±54.6bc18.2±1.5b437.8±40.0abc1986.5±124.3ab。。0.075%~0.25%11.8%~15.9%[4]。P0.01。。[5]。。3.22。。Little[3]NLCPAR。2。Kratzer[6]13NLCPARNLSPAR。Piepho[7]NLSPARP=0.02P=0.01P0.05。Sauer[8]46/3DLMDL-MHA-CaAA7~21d7~42dP0.05。4DLMDL-MHA-CaAA3720104615·NutritionandFeedstuffs1DL-MHA-Ca71%7~21d2DL-MHA-Ca66%7~21d/3DL-MHA-Ca63%7~42d4DL-MHA-Ca58%7~42d/5DL-MHA-Ca74%6DL-MHA-Ca60%8DL-MHA-Ca71%7DL-MHA-Ca49%3820104615NutritionandFeedstuffs·RelativeBioefficacyofDL-MethionineHydroxyAnalog-CaSaltComparedtoDL-MethionineinBroilerChicksLIBo1,2,WUShu-geng2,ZHANGHai-jun2,YUEHong-yuan2,QIGuang-hai2*(1.KeyLaboratoryofFeedBiotechnologyofMinistryofAgriculture/FeedResearchInstitute,ChineseAcademyofAgriculturalSciences,Beijing100081,China2.BeijingAnimalSanitationSupervisionInstitute,Beijing100044,China)Abstract:AstudywasconductedtoassesstherelativebioefficacyofDL-Methioninehydroxyanalog-Casalt(DL-MHA-Ca)andDL-Met(DLM).Exponentialregressionanalysiswasusedtodeterminebiologicalefficacybasedonbody81%79%2Little[3]NLCPARNLSPAR。Little[3]NLCPARDL-MHA-CaDLM。3.3DL-MHA-CaDLM。[910]DL-MHA-Ca/。4DLMDL-MHA-Ca。7~21DL-MHA-CaDLM71%66%/7~4263%、58%/、74%、60%、49%、71%72%。[1]AOAC.Officialmethodsofanalysis(17thed)[M].ArlingtonVA:AssociationofOfficialAnalyticalChemists,2003.[2],,,.[J].,2004,37(5):751-755.[3]LittellRA,HenryPR,LewisAJ,etal.EstimationofrelativebioavailabilityofnutrientsusingSASprocedures[J].JAnimSci,1997,75:2672-2683.[4],,,.[J].,2005,26(18):12-14.[5]HuyghebaertG,PackM.Theeffectsofdietaryproteincontentadditionofnonessentialaminoacids,anddietarymethioninetocystinebalanceonresponsestodietarysulphuraminoacidsinbroilers[J].PoultSci,2006,85:947-954.[6]KratzerDD,LittellRC.Appropriatestatisticalmethodstocom-paredoseresponsesofmethioninesources[J].BritPoultSci,1996,37:623-639.[7]PiephoHP.Acautionarynoteonappropriatestatisticalmethodstocomparedose-responsesofmethioninesou