生物相容性聚氨酯支架材料的研究

242Vol.24,No.220082POLYMERMATERIALSSCIENCEANDENGINEERINGFeb.20081,2,2,1,1,2(1.(),,610065;2.,610041):,SEM,,,,,SEM,,,,:;;:TQ323.8:A:100027555(2008)0220144204:2007207204:(NCET20720583)(06ZQ0262032):,,E2mail:[e-mail],,[1],,[2][3],Yang[4],,,,,,11.14,42(MDI):;(PPG):Tdiol21000,;1,42BDO:;(C6H12N26H2O);:;:8518;:Ortegol2501,Degussa1.21201h,MDI(NCOOH)1.051,801hMDI,BDO,90,,1.3,,,,(XSZ2HS3)(SEM,JSM25900LV)1.424,PBS2d,L2DMEM3d,FBS,372hM2210B4,20mL,375%CO24h6h,L2DMEM(10%FBS,100U/mL,100mg/mL,0.29mg/mL,3mg/mLHEPES),375%CO23d,2,,,,,,,2.1,,Fig.1Fig.2Fig.2Theeffectofthecellopenercontentontheporediameter,,,,,0.2%,340m,1%,500m,,,2.2,,,5412:,,Ortegol2501,Fig.3,Fig.4,,,,,,,,,1.22%,,2.3SEMFig.5(0.4%,2.22%)SEM,,,,,,,,,,,,,,,,6412008(a)75(b)100Fig.5TheSEMphotosofPUscaffold2.4,,(Fig.6),M2210B4(),,,PU,,,(a)(b)(c)Fig.6PhotosofcelladhesionandpropagationonPU3,;,,SEM,,,,M2210B4,,,:[1]GhafourEEA.Desalination,2002,153:149l53.[2]KelleZEH,HoB,WilliamsKD.Desalination,2003,157:209216.[3](ZHAOHong2sheng),(CAIHai2bo),(PANZhao2qi),.(JournalofFunctionalPolymers),2005,18(3):361367.[4]YangL,KoromS,WeltiM,etal.Eur.J.CardiothoracSurg.,2003,24(2):201207.(151tobecontinuedonP.151)7412:[4](WANGDong),(QIHong2jin).(CottonTextileTechnology),2002,1(1):1719.[5](SUNYin2jie),(MALin),(QIHong2jin).(PolymerMaterialsScience&Engineering),2003,7(4):188191.[6](StatisticsGroupofCASMathGraduateSchool).(CommonMathematicalStatistics).(SciencePress),1979.[7]CassieA,BaxterS.Trans.FaradaySoc.,1944,40:546551.[8]MathiasE,MillerGH.TheJouralofPhysicalChamistry,1967,8:26712675.[9]GiegengackH,HinzeD.Phys.Stat.Sol.A,1971,8(2):513520.[10]PrattIH,LausmanTC.ThinSolidFilms,1972,10:151154.MagnetronSputteringUsedtoPrepareFluorocarbonCoatingsDepositedonPETFabricsHUANGMei2lin,DIJian2feng,QIHong2jin(WuyiUniversity,Jiangmen529020,China)ABSTRACT:FluorocarboncoatingsdepositedonPETfabricswerepreparedbymeansofmagnetronsputtering,andeffectsofparameters(typeoffabric,power,pressure,temperature)ontheappliedpropertiesofthosefluorocarboncoatingswerestudied.ThewaterproofcapabilityandultravioletresistanceofthePETfabricsaftersputteringweretestedandanalyzed.Resultsindicatethatthefilmthicknessincreaseswhensputteringtimeincreasesandhencethewaterproofandultraviolet2resistanceofthesampleincreases.Duringagivensputteringtime,theincreaseinpowercanleadtoincreaseinwaterproofandultraviolet2resistanceofthesample,buttheeffectofpowerisnolongerobviousasthethicknessreachestoacertainvalue.Keywords:magnetronsputtering;PET;PTFE;fluorocarboncoating(147continuedfromp.147)StructureandCellCompatibilityofBiocompatiblePolyurethaneScaffoldsWANGXue2li1,HOULi2,TANJing2,TANGKe2qin1,XIAHe2sheng1,LIUTing2(1.StateKeyLab.ofPolymerMaterialsEngineering,SichuanUniversity,PolymerResearchInstituteofSichuanUniversity,Chengdu610065,China;2.TheHematologyResearchLaboratoryofWestChinaHospital,SichuanUniversity,Chengdu610041,China)ABSTRACT:Polyurethanescaffoldswerepreparedviapre2polymerization.Theinfluencesofcellopenerandfoamstabilizeronthestructureofscaffoldwerestudied.Theresultsshowthatasthecontentofthecellopenerincreased,theporediameterbecomeslarger.Whilethecontentofthestabilizerincreasedtheproediameterandthefoamdensitydecreases,buttheporevolumeratioincreases.SEMphotosshowthatthecellsofthePUscaffoldsareinterconnected.Finallythegrowthofcellscanscaffoldswasobserved.Thecellscanadhereandsecreteextra2cellularmatrixandgrowonPUthree2dimensionalscaffolds.ThePUscaffoldshavegoodcellcompatibility.Keywords:polyurethane;scaffold;cellcompatibility1512: