抗菌药的常见药物相互作用

!#$%&’&(()##($*((+(&)((,&)(+*(((-(./012345/674893.2’+.2’.2’.2’.2’.2’.2’.2’:;+’-.2’&=94883.2’:;+’-:;:;+’-.2’*&,?+:;.2’*-*),.2’&+-@#A#.2’-!#$%&’()*+’,&*.2’$8345/364893639/B98C5A/64892D!,#.2’-664/9E9F6783:6*G=1*GH3*G’+G=1*G:6*G.2’.2’&(.2’&&I5+G&&)&*&,*((+**$+&:J836K23E574:J5B94J5/I5L%*((+M9%+D9%&!#$%&’()*+!#,!$!#)*+!#,!$--./!-/!%0!%-/1./234%(!234%(!5!./6./%.%./%!/%.%!*%6!67&’(5&’(&’(8%6(92%-/’:;-%.7&’(,-.=!5%.67’:;%!%%)*+%#2346(#&’(%-*%1%,)*+2346(#!285..=&’(6%5234!28-%8!7’:;&’(-,7%#75?@*+?4&’(5?@*+?4’:;?@*+?4%’:;?@*+?4(A6B2C!B?=!BDE6B!-!..6!!56%2$FGCH’GIEJK2$ELK$EMDENO!..6PLAO6:LO%!#$%&’()*+(,-.%$’()*+(,/0123,/0123,.1423,-1%%546$/01/01789:;8=68-!?*+@%-789:;8=6823,.14?*+%-1A2-,8BC,(=DD8+(CE8C=FG,&=BH=I:J8CI6BKLC8B=IC:M:;H=IB:F68MNG2F,&=BH=I:J8C-OO%%.-P*-.-%Q=&=C=(G/BKLC8B=IC:MRC&=DC&B:HSI=6C&8H=IB:F68M=:T8BT8RNGN1CHIB:U=F2&8H:C&8B-OOP.@’KVVF2’-..*-4%.W=CJMX’,:FJYE’C:CJ=NZG/BKLC8B=IC:M:;H=IB:F68M8H*V&=MM:6BC&B:HSING1,&=BH=I:C&8B-OO@.-.4O*.!P4X:Y:M8MC8FQ116=H/G(=IB:F68=CU=IC8B=FMG/BKLC8B=I*C:M:;IFI=FML;I=I8NG/BKL’=;8CS-OO!-.-!*-%%![:L,\W::MF8SYZ)=H=J8C=FG2&=L8MC&8V&=BH=I:J*8CIM=68F8ICB:I=B6:LB=V&IV&=BH=I:6S=HIM:;C8B;8=68RC&I:I:HC=C=6HMCB=C::;8BSC&B:HSING2F,&=BH=I:F+&8B-OO%!%%.-*%.$P]KVC=’\^=JB=1N:&M:YW8C=FG2SIF:MV:B*8BSC&B:HSI*C8B=IC:B8=FCB=MVF=CV=C8CMNG^BN2F,&=BH-O$O%@4@!*4$-@7K68BUKBLZ]G’8DKB8;:FF:RLC&8=66C::;8BSC&B:HSIC:IF:D=V*8CB8=CH8CNG1HN,MSI&=CBS-OO4-!--$4*-$4-$[:BNY[=MC8,/G/BKLC8B=IC:MRC&=CU=IC8B=F=L8CMNGN7=H,B=IC-OO!4-$-*OO/IVV8BH=\(Z:68[G7FK:B:_K:F:8M0C8B=IC:VB:;F86KBL8C8B=F=UM:BVC:NG/BKLM-OO.4!’KVVF.’P!*’@%-^:BI&8B6L’(’C8T8MYQI&:F=MY18C=FG?K:F:8M1VB=IC*I=FB8T8R:;IFI=FKM8M6:MLI:M68B=C:M=66BKLC8B=IC:MNGN7=H,B=IC-OOP4%PO*@$--(=BC’N(8S8BN(2&KIJ’\8C=FGZ8T:;F:9=I=6MV=BF:9=IQ8R_K:F:8=CU:CIMNG1,&=BHI:C&8B-OO$.%.%*.%P-%EBMC(EEBMCEN\F8VM8B(EGZ8T:;F:9=I=6CB:T=;F:9=I+&889CL88B=C::;;FK:B:_K:F:8MNG1HN[8=FC&’SMC,&=BH-OO@!4%!PO*%!$4-.^B=IJUFF(Z^=B8M2ZG[:R6:8MF8T:;F:9=II:HV=B8C::C&8B=*CU:CIMGA’,&=BH=IMC-OO@$.*O-4/KV:C[+HMCN7’:KR88^8C=FG+:BM=68M68V:C8VB:U=UFSB8F=C86C:MV=B;F:9=INGEKBN2F(IB:U:F0;8IC/M-OOP-!.!*.!--!X:(:FCJ8ZZ]B88UF=CC/N/K=’‘8C=FG0&UC::;C8B;8=*68H8C=U:FMHTCB:US=D:F8=C;KL=F=L8CM=6USM8F8ICT8M8B:*C:B8KVC=J8&UC:B=C68VB8MM=CMY8F=C:C:V&=BH=I:J8CI*C8B=IC:MTT:NGN2F,MSI&:V&=BH=I:F-OOP-P-4*--%-PQ8KT:8,NN=F=T=\(G0CB=I:=D:F86B=MCI=FFSIB8=M8MVF=MH=I:*I8CB=C:M:;F:T=MC=C=6F:T=MC=C=I6NG2F,&=BH=I:F+&8B-OOPP!4*P--@+&:HVM:/aMC8B]GAM8:;C8B;8=68=6I:CB=6I=C866BKLMNGN1(1-OOP%@!-..O*-.4--$Q8RU8BBS/Z^=MM’Q(U=8;:2a8C=FG1;FKI:=D:F8b=HCBVCS*F86BKLC8B=IC:C&B88H=F8=6KFCMNG2F0;8IC/M-OO@%4%@*%@--O’F=KL&CIBYZE6R=B6M/NGY8I8C=6T=I8MC&8ISC:I&B:H8,4!8*DSH8MNG1,&=BH=I:C&8B-OO!%OP-O*P%4%XI8CN+8LY/:L:F:Z28C=FGE;;8IC:;CB:T=;F:9=I=8R;FK:B:_:F:8=CU:CI:C&8MC8=6S*MC=C8V&=BH=I:J8CIM:;C&8:*V&SFF8&8=FC&ST:FKC88BMNGN1CHIB:U=F2&8H:C&8B-OO@.O$-*$P%-,&SMI=M/8MJY8;8B8I8(G!%6E6C:G(:CT=F8QN(86*I=FEI::HIM2:HV=S0I-OO$%-@!*%-@O%%*!*%-.!%.%%$.-2&=N0;8IC2&8H:C&8B78UG%.X:FG.Q:G-