电针头穴对血管性痴呆患者认知功能及生存质量改善的临床研究

:(:0203LP445):,,19601;;:(,610075)::,,:90,6MMSEADL2R:3,VD;;,3,:;;MMSE;ADL2R:R24519;R543:A:100420668(2006)032006206ClinicalResearchonCognitionLevelandLivingQualityofVascularDementiaByScalpElectricAcupunctureZHANGHong,ZHAOling,ZHUMan2jia,FANGYong2jiang(ChengduUniversityofTCM,ChengduSichuan,610075)Abstract:Objective:Investigatetheclinicaleffectofscalpelectricacupunctureoncognitionlevelandlivingqual2ityofvasculardementia,andapplytheevidenceforclinic.Methods:90patientswereinvolvedinthistrial,anddivid2edinto3groups.PatientsindruggroupweretreatedwithNimodipine,acupuncturegroupweretreatedwithscalpelectricacupuncture,andthelastgroupwereaddingscalpelectricacupuncturewithNimodipine.EverygroupmeasuredMMSEandADL2Rmeasuringscale,andthenrechecked6weekslaterwhentreatmentcoursewerecompleted.Resultsandcon2clusion:Theentiregroupshadeffectontreatingcognitionlevelandlivingquality,buttherewerenosignificantdiffer2encesbetweenthem.Allofthegroupcanevidentlyimprovetheabilityofcognition,memory,operate&visual2spaceskill;druggroupandacupuncture2druggrouphadbettereffectonverbalability.Thereweresignificantdifferencesbe2tween3groupsonmemoryability,andscalpelectricacupuncturegroupwithNimodipinewasthebest.Keywords:scalpelectricacupuncture;vasculardementia;MMSEscale;ADL2Rscale(Vasculardementia,VD),6JournalofChengduUniversityofTCM20069293Sep12006,Vol129,No13,[1],VD324/10,VD420[2],,55VD,VD,,VD11112004220061,90,,311211211(1)DSM2IV[3],6;(2)1993(NINDS/AIREN)[4];(3)(HIS)7;(4)(CDR)(CDR=110)(CDR=210);(5)4580,,1;(6),,,11212(1),DSM2IV;(2)(HIS)7;(3)(CSDD)[5]8,DSM2IV,;(4),,;(5)45,80,2211SAS,,90,0190903,()()(,),212,,,,21321311(1):(20mg/,,:H14022821)(2):301115()(3):G6805()21312(1):,,(2):,:()(3)::,75%,1530115,,015112,,,0151,G6805,,300/min500/min,,1;11,,,;,;,;,;30min,1,5(),6,30:,20mg/,3/d,6,:2143721411(1):;(2);(3)111214122141211(MMSE),12;MMSEMMSE3030,,:();();()():20,242141212(ADL-R),12;ADL2R20,;20,1,24;20,,,,,(Kappa),Kappa01850190,3311,:20%;:12%;:12%;:212%=(-)/100%=(-)/100%312SPSS1210,,,q;(Mann2Whit2neyTest),,,P010531390,73,17(611,)73,79,9031311141/2817/11621964617412415/96412501010792719/8671556619632=01624F=21406P0173200109722P288124411168201069524461312799633HISCDR=1CDR=2HIS2822611164321248242041212081184127225111296214782=01196Z=-01577P01906501563713,3HIS(P0105)4MMSEADL2RMMSEADL2R281917865129443196413162024191792411604613751210322718192641763491444151468Z=-11382Z=-11020P0116700130784,3MMSEADL2R(P0105),,,3MMSEADL2R,3,,(P0105)820062931312313121135,5p6,653MMSE(FAS)nZP2811(3913%)5(1719%)12(4219%)2410(4117%)7(2912%)7(2912%)-110500129392713(4811%)7(2519%)7(2519%)7934(43%)19(2411%)26(3219%)53MMSE(PP)nZP2411(4518%)5(2018%)8(3313%)2310(4315%)7(3014%)6(2611%)-015460158482613(50%)7(2619%)6(2311%)7334(4616%)19(26%)20(2714%)55,3(P0105)63ADL2R(FAS)nZP287(2510%)5(1719%)16(5711%)249(3715%)2(813%)13(5412%)-118000107182712(4414%)6(2212%)9(3313%)7928(3514%)13(1615%)38(4811%)6p3ADL2R(PP)nZP247(2912%)5(2018%)12(50%)239(3911%)2(817%)12(5212%)-114360115112612(4612%)6(2311%)8(3018%)7328(3814%)13(1718%)32(4318%)66p,3(P0105)3131212MMSE711,7p11p7MMSE(FAS)n(P)281917865129423139341349316073117801000241917924116023108331900312922138601000271819264176322174151208318152120201000F=01251P=017787pMMSE(PP)n(P)241917505166623195841369412083103601000232011303190023156531174314352133201000261818464183922180851299319622110701000F=01579P=0156377p,3MMSE(P0105),MMSE(P0101)8MMSE(FAS)n(P)2891679411731117503107521071213870100024101083217331210832150121000118880100027918152181511151931018117041172801000Z=-01026P=0197958pMMSE(PP)n(P)2491750414751211673107421417214120100023101304215661213912103921087118810100026918462186611161531034117691172801000Z=-01602P=01547488p,MMSE3(P0101),(P0105)9MMSE(FAS)n(P)283171411243413211136201607111000100024315001118041167111290166701761010002731037115314125911259112220189201000Z=-21464P=010137:P0105399pMMSE(PP)n(P)243162511279413331143501708111600100723315651116141261110540169601765010002621923114404119211234112690187401000Z=-21052P=010401:P010599p,MMSE3(P0101),3(P0105),(P0105)10MMSE(FAS)n(P)283142901836319640179301536018810100324313750177031542018840116701565011622731259017643166711038011670156501019Z=-01083P=01933510pMMSE(PP)n(P)243141701881410420180601625019240100323313910178331565018960117401576011622631269017783169211050011740157601019Z=-01411P=0168121010p,MMSE3(P0105),(P0101),(P0105),(P0105)11MMSE(FAS)n(P)284117901945416430173101464019620101724410421145941417110600137501647010092731815112104133311414013750164701001Z=-01632P=01527111pMMSE(PP)n(P)244116711007417080175101542110210101623410871147441478110390139101656010092631808112344134611441013910165601001Z=-01313P=0175411111p,MMSE3(P0105),(P0105)7113MMSE(P0105),MMSE(P0101)3(P0101),(P0105)3(P0101),3(P0105),(P0105)3(P0105),(P0101),(P0105),(P0105)3(P0105),(P0105)3131213ADL2R1212p12ADL2R(FAS)n(P)284319641316203712501113756171491128010012446137512103239166711171361708618110100027491444151468401963141493814816163501000Z=-11706P=010881020062912pADL2R(PP)n(P)2444137514168536154212113