长效蛋白药物研究进展

长效蛋白药物研究进展作者：吴军，马清钧作者单位：军事医学科学院生物工程研究所,北京,100071刊名：生物产业技术英文刊名：BIOTECHNOLOGY&BUSINESS年，卷(期)：2009(3)参考文献(25条)1.DHalpernWG;MigoneTS;WangQPharmacokineticsandinvitroandinvivoanti-tumorresponseofaninterleukin2-humanserumalbuminfusionproteininmice[外文期刊]2005(06)2.Humangenomesciencesannouncespositiveresultsofphase2Btrialofalbufcron3.NelsonD;RustgiV;BalanVSustainedvirologicresponserateswithalbumininterferonalfa-2bincombinationwithribavirininnon-responderstopriorinterferontherapy:intcrimresultsfromaPhase2study20064.ZamhoniWCPharmacokineticsofpegfilgrastim2003(08)5.MolinenxGThedesignanddevelopmentofpegfilgrastim(PEGrmetHuG-CSF,Neulasta)2004(11)6.ReddyKRDeveloprnentandpharmacokineticsandpharmacodynamicsofpegylatedinterferonalfa-2a(40kD)2004(z2)7.YaoZ;DaiW;PerryJEffectofalbuminfusiononthebiodistributionofintcrleukin-2[外文期刊]2004(05)8.MeldcrRJ;OsbornBL;RiccobeneTAphase2studytoevaluatetheantiviralactivity,safety,andpharmacokineticsofrecombinanthumanalbumin-interferonalfafusionproteiningenotype1chronichepatitisCpatients[外文期刊]2006(04)9.MüllerD;KarleA;MeissburgerB;etalKontermannREImprovedpharmacokineticsofrecombinantbispecificantibodymoleculesbyfusiontohumanserumalbumin[外文期刊]2007(17)10.StorkR;ZettlitzKA;MüllerD;RetherM,HanischFG,KonterrnannRENglycosylationasnovelstrategytoimprovepharmacokineticpropertiesofbispecificsingle-chaindiabodies[外文期刊]2008(12)11.Keytrialsoforganon'sCTPtechnologyachieveclinicaltrialmilestone12.FaresF;GanemS;HajoujTDevelopmentofalong-actingerythropoietinbyfusingthecarboxylterminalpeptideofhumanchorionicgonadotropinbeta-subunittothecodingsequenceofhumancrythropoietin[外文期刊]2007(10)13.ChemmanurAT;WuGYDrugevaluation:Albuferon-alpha-anantiviralinterferon-alpha/albuminfusionprotein[外文期刊]2006(08)14.ChisholmPL;WilliamsCA;JonesWETheeffectsofanimmunomodulatoryLFA3-IgG1fusionproteinonnonhumanprimates1994(04)15.WemhlattME;KremerJM;BankhurstADAtrialofetanercept,arecombinanttumornecrosisfactorreceptor:Fcfusionprotein,inpatientswithrheumatoidarthritisreceivingmethotrexate[外文期刊]1999(4)16.RyanSM;MantovaniG;WangXAdvancesinPEGyationofimportanthiotechmolecules:deiveryaspects2008(04)17.Profile2008ofpharmaceuticalindustry18.BukowskiRIM;TendlerC;CutlerDStatkevichP.TreatingcancerwithPEGIntron:pharmacokineticprofileanddosingguidelinesforanimprovedinterferon-alpha-2bformulation2002(02)19.FaresFA;SuganumaN;NishimoriK;etal,BoimeIDesignofalong-actingfollitropinagonistbyfusingtheC-terminalsequenccofthechorionicgonadotropinbetasubunittothefollitropinbetasubunit1992(10)20.MannaertsBMPharmacodynamicsofasinglelowdoseoflong-actingrecombinantfollicle-stimulatinghormone(FgH-carboxyterminalpeptide,corifollitropinalfa)inwomenwithWorldHealthOrganizationgroupⅡanovulatoryinfertility2004(12)21.GlaspyJPhaseⅢclinicaltrialswithdarbepoetin:implicationsforclinicians200522.ElliottS;BrowneJControlofrHuEPObiologicalactivity:theroleofcarbohydrate[外文期刊]2004(12)23.HoltLJ;BasranA;JonesKAnti-serumalbumindomainantibodiesforextendingthehalf-livesofshortliveddrugs[外文期刊]2008(05)24.StorkR;MüllerD;KontcrmannREAnoveltri-functionalantibodyfusionproteinwithimprovedpharmacokineticpropertiesgeneratedbyfusingabispecificsingle-chaindiabodywithanalbumin-bindingdomainfromstreptococcalproteinG[外文期刊]2007(11)25.ZhangM;McDonaldP;WongWLT;DamicoLA,DennisMSAlbuminBindingasaGeneralStrategyforImprovingthePharmacokineticsofProteins[外文期刊]2002(38)本文读者也读过(5条)1.丁宏标.刘建平.李富伟.高秀华.杨禄良.徐俊宝植酸酶的基因工程研究与工业化生产应用[期刊论文]-中国饲料2003(21)2.卫广森.陆承平.陈溥言.王卓.孙宇新生仔猪大肠杆菌性腹泻K88ac-ST1-LTB三价基因工程灭活疫苗工业化生产工艺的研究[会议论文]-20063.苏世振融合基因anti-erbB2scFv-Fc-CD28-CD3(ζ)的重新优化构建及真核表达[学位论文]20104.杨晓峰.李曼尼.温国华丙烯腈接枝共聚对多肽分子的功能化修饰机理[期刊论文]-石油化工2005,34(z1)5.郭丽颖.王慧嫱抗风湿性关节炎新药——依他奈特[期刊论文]-中国药学杂志2001,36(1)本文链接：