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1、PartILivingintheMicrobialWorldInthispart...Iexplorethebasicsofhowbacteria—goodandbad—impactyourbodyanditsfunctions.Fromyourimmunesystemtoyourintestines,bacteriaaffectyourhealthinnumerousways.Understandingthebasicsofthatimpactwillhelpyouunderstandhowprobioticscanhelpyounotonlyachievebetterhealthbutalsofightsomediseases.Lastly,Ihelpyouunderstandwhatprobioticsareandwhatyou’lllookforasyouincorporatethisimportantsup-plementintoyourdiet.Chapter1GettingaHandleontheTrueNatureofBacteriaInThisChapter▶Exp。
2、loringthediscoveryofbacteriaandtheirroleinhealth▶Lookingattheconnectionbetweenbacteriaandbraindevelopment▶Investigatingbacteria’sroleinmoodandanxietyTheUnitedStates,theworldleaderinsomanyotherareasofhealthandmedicalscience,isconsideredan“emerg-ingmarket”inthedevelopmentanduseofprobiotics;suchsupplementsarefarmorepopularinEuropeandAsia,andprobiotic-richfoods(seeChapter11)arestaplesinmanyculturesaroundtheglobe.Interestingly,accordingtotheNationalHealthInterviewSurveyconductedbytheNationalInstitute。
3、sofHealth’sNationalCenterforComplementaryandAlternativeMedicine(),Americansuseprobioticsfortheirchildren,butnotforthemselves.Certainly,childrencanbenefitfromprobiotics(seeChapter8),butresearchindi-catesthatprobioticsareappropriateforgrown-upstoo.Evenhealthyadultscanhelpmaintaintheirgoodhealthbytakingprobiotics.Asinothercountries,yogurtmanufacturersintheUnitedStateshavelongtoutedthebenefitsofliveculturesofbacte-riaintheirproducts.Morerecently,companieslikeDannonhavebegunaggressivelymarketingyogur。
4、tanditsfriendlybacteriaasawaytoregulateyourdigestivesystem—andtheybackuptheirclaimsbyfinancingorconductingclinicalstudies.PartI:LivingintheMicrobialWorld10TheNationalCenterforComplementaryandAlternativeMedicinealsohasmadeprobioticresearchahighpriorityforfundingprojects.Thecentersupportsresearchonusingprobioticstoalleviateorpreventvariousgastrointestinaldisordersininfantsandchildren;treatingandpreventingantibiotic-relateddiarrhea(seeChapter4);andimprovingtheefficacyoffluvaccines.Governmentandpriv。
5、atelyfundedresearchisturninguplotsofevidencethatprobioticscandomorethanregulateyourdigestivesystem.Iprovideinformationonvarioushealthapplicationsforspecificprobioticstrainsthroughoutthisbook.Butresearchersalsoareuncoveringfascinatinglinksbetweenthebacteriainyourdigestivesystemandyourbrain’sdevelopment,aswellasmentalhealthissueslikeanxietyanddepression,whichIdiscusslaterinthischapter.First,though,thenextsectionprovidesabriefoverviewofthetheoriesanddiscoveriesaboutbacteria’sroleinsicknessandhealth。
6、.ExploringtheHistoryofBacteriaTheoriesandPracticesCenturiesbeforetheinventionofthemicroscopeenabledresearcherstoobservelivingorganismsthatareinvisibletothenakedeye,somescientiststheorizedthattinycreaturesspreaddiseaseamonganimalsandhumans.AncientHindutexts,forexample,refertolivingagentsascausingdisease.In36BCMarcusTerentiusVarrowarnedagainstbuildinghomesandfarmsnearswampsbecausesuchareasbreed“certainminutecreatures,whichcannotbeseenbytheeyes,whichenterthebodythroughthemouthandnoseandtherecausese。
7、riousdiseases.”Evenso,conventionalwisdomdiscountedtheideathatorgan-ismslikebacteria,orgerms,causedillness.Theprevalenttheorywasthatdiseasegeneratedspontaneously.EvenAntonvanLeeuwenhoek,consideredthefatherofmicrobiology,didn’tconnecttheorganismshesawunderhismicroscopewithdisease.Andtheideathathumancontactcouldtransmitharmfulmicroorganismsmetwithmassiveresistanceamongthemedicalandscientificcommunities.Chapter1:GettingaHandleontheTrueNatureofBacteria11Inthefollowingsections,Iprovideabriefoverviewof。
8、howthegermtheoryofdiseasedevelopedandthehistoryofusingprobiotics,orgoodbacteria,topromotegoodhealth.UnderstandinggermtheoryAlthoughitformsthebasisofmedicaltreatmentandhygienepracticestoday,germtheory—theideathatmicroorgan-ismsareresponsibleforcausingandspreadingillness—wasquitecontroversialforcenturies.Beforetheinventionofthemicroscope,mostpeople(includingmostdoctorsandscien-tists)believedthatdiseaseeitherarosespontaneouslyorwasspreadthrough“badair,”ormiasma.IgnazSemmelweis,aHungarianobstetricia。
9、nworkingataViennahospitalin1847,noticedthatwhendoctorsandmedi-calstudentsattendedbirths,newmotherswerefarmorelikelytodieofpuerperalfever,commonlyknownaschildbedfever,thanwomenwhodeliveredtheirbabiesathomewiththeaidofamidwife.Semmelweisobservedthatdoctorsandmedicalstudentsatthehospitaloftendeliveredbabiesrightafterperformingautopsies,andheinsistedthatdoctorswashtheirhandsinachlorinatedsolutionbeforeexaminingpreg-nantwomen.Thiselementarytechniqueloweredthechildbedfeverdeathrateatthehospitalfromnea。
10、rly1in5toabout1in50.EnglishphysicianJohnSnowaddedevidencesupportingthegermtheorywhenhetracedtheoriginsofacholeraout-breakinLondoninthe1850s.Snownoticedthatthehomesofpeopleaffectedbytheoutbreakallgottheirwaterfromthesamepump,andheidentifiedthatwaterasthemechanismforspreadingthedisease.Inthe1860s,LouisPasteurconductedexperimentsthatprovedthatlivingorganismsinfreshlyboiledbrothcamefromoutsidethebrothratherthanspontaneouslygenerat-ingwithinit.Adecadelater,JosephLister(forwhomtheLi。
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