MRI技术发展十年回顾

MRI冯晓源复旦大学医学院附属华山医院放射科(上海200040)2003MRI,11,,C(PaulCLauterbur)(PeterMansfield),30PaulLauterbur,1976,PeterMansfield1980,MRIFonar,,1984FDA,1901X1979CT,21,MRI,;,10MRI,MRI,,,,,MRI,,,,MRI90,90,;,MRIMRI,MRI,,90,MRI?,MRI0.3-1.0T,1.5T;10mT/m,1.5TMRI15mT/m10-35T/m-s,,1-2s,,MRI,CT,,T1,90,MRI,,MRI,EPI20-40mT/m,0.5ms,100T/m-s90MRI15mT/m,50T/m-s,EPI90119!2006272,,MRI20mT/m,100T/m-sMRI,MRI,MRIMRI1.,,0.5T1.0T,1.5T1996,4K0.5T,(),,,,,,,,,1.4MRI,MRI,MRI,MRI,,,,,,,,,,,,,,,1.5m,,,,,CT,,,1995,,,1995,BrighamandWomen∀sFerencJolesz,360,#∃,,1999,0.7T,2004RSNA,1.0T,3.0T,MRI,,1991,FJDavies2.0T,MRI1.5T,,2.0T,,,3.0T4.0T,,3.0T,,3.0TMRI400KeithR.Thulborn9.4T120!2006272,,4.7T7T8T,:,,2.MRI1973PaulLauterburPeterMansfield90,PeterMansfield1991#∃,1994(EPI)#∃,,,1995,HORIZON#∃,,,,#∃1998,,:,,,,,,PaulRHarvey1996,,,,2000,,#∃(),,,,3.1983,,50%,SNR()40%,,90RoemerPB#∃,,,,MRI,,,,,,,2002,#∃#∃,MRI#∃#∃,,2003Tim,,76,32,,(),205,Tim4.1986J.Hennig,Magn.Reson.Med.!RARESEk121!2006272MRSEMR(FSE)J.HennigFSE,2003MaxPlanckResearchAwardforBiosciencesandMedicineMRIEPIPeterMansfield197890EPIEPIMRI1999,(ETH)PruessmannKPk--SENSE,,/,,,,PipeJG#∃(PROPELLER),K,,,,,,1996,Kai-YiuHo,M.D.,MRI19995,,MobiTrak(MovingBedImaging-),,,,MRI,MRI1985,LeBihanMRI1990,MichaelMoseley,,MRI,DiffusionWeightedImaging,EPI1993,OgawaSEPI,(fMRI),,1996,fMRI1994BasserdiffusiontensorimagingDTI,,80,MansfieldEPI,90,AtkinsonDJ,,1998,WielopolskiPA,MRI,,,,:1JoleszFA,KikinisR.Intraoperativeimagingrevolutionizestherapy.DiagnImaging(SanFranc).1995Sep;17(9):628.2LaatschLK,ThulbornKR,KriskyCM,etal.InvestigatingtheneurobiologicalbasisofcognitiverehabilitationtherapywithfMRI.BrainInj.2004Oct;18(10):95774.3Mansfield,P.Multi-PlanarImageFormationusingNMRSpinEchoes.J.Phys.C.197710(3):5558.4HarveyPR,KatznelsonE.Modulargradientcoil:Anewconceptinhigh-performancewhole-bodygradientcoildesign.MagnResonMed.1999Sep;42(3):56170.5RoemerPB,EdelsteinWA,HayesCEmetal.TheNMRphasedarray.MagnResonMed.1990Nov;16122!2006272(2):192225.6HenningJ,NauerthA,FriedburgH.RAREimaging:afastimagingmethodforclinicalMR.MagnResonMed.1986Dec;3(6):82333.7PruessmannKP,WeigerM,ScheideggerMB,etal.SENSE:sensitivityencodingforfastMRI.MagnResonMed.1999Nov;42(5):95262.8PipeJG.MotioncorrectionwithPROPELLERMRI:applicationtoheadmotionandfree-breathingcardiacimaging.MagnResonMed.1999Nov;42(5):9639.9HoKY,LeinerT,deHannMW,etal.Peripheralvasculartreestenoses:evaluationwithmoving-bedinfusion-trackingMRangiography.Radiology.1998Mar;206(3):68392.10LeBihanD,BretonE,LallemandD,etal.MRimagingofintravoxelincoherentmotions:applicationtodiffusionandperfusioninneurologicdisorders.Radiology.1986Nov;161(2):4017.11MoseleyME,CohenY,KucharczykJ,etal.Diffusion-weightedMRimagingofanisotropicwaterdiffusionincatcentralnervoussystem.Radiology.1990Aug;176(2):43945.12MoseleyME,CohenY,MintorovitchJ,etal.Earlydetectionofregionalcerebralischemiaincats:comparisonofdiffusion-andT2-weightedMRIandspectroscopy.MagnResonMed.1990May;14(2):33046.13OgawaS,MenonRS,TankDW,etal.Functionalbrainmappingbybloodoxygenationlevel-dependentcontrastmagneticresonanceimaging.Acomparisonofsignalcharacteristicswithabiophysicalmodel.BiophysJ.1993Mar;64(3):80312.14BasserPJ,MattielloJ,LeBihanD.MRdiffusiontensorspectroscopyandimaging.BiophysJ.1994Jan;66(1):25967.15AtkinsonDJ,BursteinD,EdelmanRR.First-passcardiacperfusion:evaluationwithultrafastMRimaging.Radiology.1990Mar;174(3Pt1):75762.16WielopolskiPA,vanGeunsRJ,deFeyterPJ,etal.Breath-holdcoronaryMRangiographywithvolume-targetedimaging.Radiology.1998Oct;209(1):20919.(收稿日期:20051015),,,,,,,2,83%,67.5%,,,,,,,,,123!2006272