文献查阅SciFinder

文献查阅21、SciFinder的使用2、Beilstein的使用SciFinder-ExplorebyChemicalSubstance3SciFinderoffersavarietyofwaystofindchemicalsubstances:chemicalstructure,chemicalname,CASRegistryNumbers®,ormolecularformula.BeginbyclickingExplore.4ClickChemicalSubstanceorReaction.5ClickChemicalStructure.6Usethetoolpalettetodrawachemicalstructure.ClickGetSubstances.Note:ByclickingAdditionalOptionsyoucannowtakebetteradvantageofCAS'vastsubstanceinformationbyincludingorexcludingsubstanceclassesfromyoursearchwithSciFinder.7Severalsubstanceresultsaredisplayed.Toviewdetailsforasubstance,clickaMicroscopeicon.8Additionaldetailsaredisplayed.Scrolldownthedetailedrecordtoseetheassociatedcalculatedandexperimentalpropertydata.ClicktheCommercialSourcesicontofindouthowtopurchasethesubstance.9SciFinderlistschemicalsupplierinformation.ExplorebySubstanceIdentifier10ExplorebySubstanceIdentifierallowsyoutofindsubstancesbasedonanameorCASRegistryNumber®.ClickSubstanceIdentifier.11Typeachemicalname,tradename,orCASRegistryNumber(oneperline).ClickOK.12ClicktheMicroscopeicontodisplaymoredetails,includingalternatesubstancenames.13Thedetailsaredisplayed.ExplorebyMolecularFormula14Tobegin,clickMolecularFormula.15Enteramolecularformula.Onlyonemolecularformulamaybeenteredpersearch.ClickOK.16SciFinderretrievessubstanceswiththespecifiedmolecularformula.ClicktheMicroscopeiconnexttoasubstancetodisplaysubstancedetails.17Clickanyofthesebuttons(ifavailable)foradditionalinformation.Referencesforthesubstance3DmodelofthesubstanceCommercialsourceinformationRegulatedchemicalslistingReactionsthatinvolvethesubstance(SciFindersubscribersonly)1819WeresearchcytidineasasubstructureofamorecomplexstructureTobegin,clickExplore20ClickChemicalSubstanceorReaction.21ThenclickChemicalStructure.22Usethetoolpalettetodrawachemicalstructure.Noticethatstereobondsmaybeincludedinyourstructure.ClickGetSubstances.Choosetoretrievesubstructureresults,andclickAdditionalOptions.23Specifythesubstanceclassesofinterest.ClickOK.24Becausethequerycontainsstereo,theresultsareautomaticallyanalyzedbystereo.Selectastereogrouporgroupsofinterest,andclickGetSubstances.25Theresultsaredisplayed.Tofurtheranalyzethisresultset,clickAnalyze/Refine.26ClickRefinetoseethenewRefineoptions.27ClickPropertyAvailability,oneofthenewrefineoptions.28Selectpropertiesofinterest.29Substancesforwhichthosepropertiesareavailabledisplay.ReactionInformation30clickExplore.31ClickChemicalSubstanceorReaction.32ThenclickChemicalStructure.33First,drawastructure.Thenaddfunctionalgroupsbyclickingthefunctionalgroupsbutton.Selectatermfromthelistoffunctionalgroups.Thenclickinthestructuredrawingwindowtodrawtheterm.Repeattodrawadditionalterms.34Drawareactionarrowfromlefttorighttoassignrolestothereactionparticipants.ThenclickGetReactions.35ByclickingonAdditionalOptions,youcannowlimityouranswersettomorerelevantreactioninformation,withSciFinder2004Edition.36SelecttheappropriatelimitsandclickOK.37Onceyougetalistofreactions,youcanviewallhitreactionsoronehitreactionperreference.Inthisexample,weviewreactionsintheCompactformatwithonehitreactionperreference.38ClickingonthemicroscopeallowsyoutoseetheFullformatforthisreaction.39Closethisviewtoreturntotheanswerset.40ClickAnalyze/Refine,thenAnalyze,todeterminethetypeofcatalystsusedinthesereactions.41SelectCatalyst,clickOK.42Ahistogramindicatesthefrequencyinwhichcatalystsareusedinthereactions.Clickonaparticularcatalysttoviewadditionaldetails.4344Toviewallofthereactionsthatusethiscatalyst,selectitandclickGetReactions.45Clickonthereferencelinktoseethebibliographicinformation.46Thebibliographicinformationisdisplayed.ExplorewithPanorama47Tobegin,clickExplorewithPanorama.48Enteratopicofinterest,andclickOK.49Selectthecandidate(s)thatmostcloselymatchyourquery.ClickOK.50Panoramaallowsyoutopre-setuptofivecategorycombinations.Forthisexample,setPreset5tocross-tabulateCatalystsvsTopics.ClickGo.51TermsrelatedtoCatalystsandTopicsdisplayinanExcelworksheet.Thenumberswithinthecellsrepresentthenumberofreferencesinyouranswersetthatareassociatedwiththetermsinthecorrespondingrowandcolumn.Toretrievereferencesforaparticularnumberedcell,double-clickthecell.52SciFinderdisplaysthereferences.53FromtheExcelworksheet,youcanalsochartrelationshipswithinthecross-tabulation.ClicktheMakeChartsbuttononthetoolbar.54Noticethattabsforchartsappearatthebottomoftheworksheet.Clickatabtoviewachart.Forthisexample,clicktheHydrogena(shortforHydrogenationcatalysts)Bartab.55Thisbarchartdisplaysthecommonlyusedhydrogenationcatalysts.