多乐氟与氟保护漆抑制固定正畸矫治中牙釉质脱矿的比较研究

多乐氟与氟保护漆抑制固定正畸矫治中牙釉质脱矿的比较研究摘要目的：比较多乐氟与氟保护漆抑制固定正畸矫治中牙釉质脱矿的临床效果。方法：收集预备接受固定矫治的临床青少年病例60例，其中男性23例，女性37例，年龄在12-18岁之间，平均年龄为14.8岁。本次研究将进行随机分组为实验组、对照组，所有患者均采取直丝弓固定矫治技术。其中，实验组1区（实验组A）前牙及前磨牙涂布Proflurid、实验组3区（实验组B）前牙及前磨牙涂布Duraphat，对照组2区（对照组A）不使用任何药物、对照组4区（对照组B）前牙及前磨牙仅涂布生理盐水，在粘托槽前、粘托槽后1月、3月、6月时涂布药物，并使用DIAG-Nodent激光龋齿检测仪测试记录数值。结果：（1）肉眼观察可见，实验组A脱矿率为23.5%，实验组B脱矿率为10.0%，实验组A与实验组B均为I度。对照组A脱矿率为62.1%，对照组B脱矿率为59.3%，对照组A与对照组B均为II度。四组之间的数值比较，X²=16.98，P＜0.05，这说明四组之间进行对比，其脱矿率不同或者不全相同。实验组A与实验组B以及实验组A与对照组A与对照组B以及实验组B与对照组A与对照组B相对比，均P＜0.05，但是对照组A与对照组B之间相对比，P＞0.05.（2）患者进行粘托槽前读数差异无统计学意义（P＞0.05），在进行粘托槽后四组患者DIAG-Nodent读数与粘托槽前比较，均具有统计学意义（P＜0.05）。组内进行LSD两两对比可以发现，实验组A与实验组B之间对比，在1个月、3个月以及6个月均具有统计学意义（P＜0.05）。对照组A与对照组B之间进行对比，两组在1个月、3个月、6个月之间的差异无统计学意义（P＞0.05），实验组A与对照组A、对照组B之间对比，差异具有统计学意义（P＜0.05），实验组B与对照组A、对照组B之间对比，差异具有统计学意义（P＜0.05），这说明使用氟化物相较于不使用氟化物效果要更好。结论：氟化物能够对患者在进行固定正畸矫治中牙釉质发生脱矿进行抑制，而且与含氟量的大小有一定的相关性，在一定范围内，含氟量较高的氟化物对于牙釉质脱矿的防治效果更佳。AbstractObjective:tocompareleprotectionfluorideandfluorinepaintmoreinhibitionoffixedorthodonticsrectificationenameldemineralizationofclinicaleffect.Methods:tocollectreadytoacceptafixedrectificationclinicalcasesofteenagers60cases,23casesofmen,women,37cases,agedbetween12to18,theaverageageof14.8years.ItthroughtherandomnumbertablemethodisdividedintotheexperimentalgroupAandgroupBandcontrolgroup,controlgroupBfourgroups,eachgroupof15cases,andthenrespectivelytakefluorineprotectivepaint,fluorine,moredonotuseanydrugsandphysiologicalsalineforpreventionandcontrol.Results:(1)theexperimentalgroupAwas23.5%,theexperimentalgroupBwas10.0%,theexperimentalgroupAandgroupBwereI.Controlgroupwas62.1%,andAcontrolgroupBwas62.1%,controlgroupAandgroupBare2degrees.Anumericalcomparisonbetweenfourgroups,Xsquared=16.98,P0.05,suggestingthatcomparisonbetweenfourgroups,thedemineralizationratedifferentornotallthesame.ExperimentalgroupAandgroupBaswellastheexperimentalgroupandthecontrolgroupandthecontrolgroupandthecontrolgroupandexperimentalgroupBBABcomparedwithcontrolgroup,P0.05,butcomparedbetweencontrolgroupandthecontrolgroupB,P0.05).(2)inpatientswithstickybracesbeforereadingnostatisticallysignificantdifference(P0.05),thefourgroupsofpatientsafterstuckbracesDIAG-Nodentreadingcomparedwithstickybracesbefore,werestatisticallysignificant(P0.05).LSDpairwisecomparisoncanbefoundinthegroup,thecomparisonbetweentheexperimentalgroupAandgroupB,at1month,3monthsand6monthsafterstatisticallysignificant(P0.05).ComparisonbetweencontrolgroupandthecontrolgroupB,thetwogroupsin1month,3months,6monthsthedifferencebetweennostatisticalsignificance(P0.05),theexperimentalgroupAandcomparisonbetweencontrolgroupandthecontrolgroupB,statisticallysignificantdifference(P0.05),thecomparisonbetweentheexperimentalgroupBandcontrolgroup,controlgroupB,thedifferenceisstatisticallysignificant(P0.05),suggestingthattheuseoffluoridethanwithouttheuseoffluorideeffectisbetter.Conclusions:inpatientswithfluoridetofixedorthodonticrectificationisenameldemineralizationofsuppressed,andthesizeofthefluoridehascertainrelevance,withinacertainrange,highfluoridefluorideinenameldemineralizationofbettercontroleffect.目录摘要.....................................................................................................................................................2Abstract..............................................................................................................................................3第一章引言....................................................................................................................................61.1概述.....................................................................................................................................61.2正畸矫治中牙釉质脱矿原因.....................................................................................61.2.1患者本身的口腔生态环境所造成的.........................................................71.2.2患者的饮食不健康所造成的......................................................................71.2.3正畸矫治器的结构也容易引起脱矿........................................................71.2.4牙齿发育状况存在着个体差异等.............................................................71.2.5粘结剂的种类不同以及对患者进行涂布的面积等...........................81.2.6其他方面............................................................................................................81.3抑制固定正畸矫治中牙釉质脱矿研究现状........................................................8第二章临床研究.............................................................................................................................92.1材料与方法.......................................................................................................................92.1.1材料.........................................................................................................................92.1.2病例资料..............................................................................................................92.1.3方法......................................................................................................................102.2观察指标........................