对苯二甲酸及其生产废水的生物毒性与控制技术张徐祥

张徐祥　程树培＊　石　磊　王　斌　朱程军　郝春博　严　俊(,210093)陆建华　喻敬周　朱建中　章晓春　王桂林　陈　骏　王洪丽(,210048)　　(TA),。TA,,。　　　　　　ControloftoxicitiesfromterephthalicacidanditswastewaterZhangXuxiang　ChengShupei　ShiLei　WangBin　ZhuChengjun　HaoChunbo　YanJun(NationalKeyLaboratoryofPollutionControlandResourceReuse,theSchoolofEnvironment,NanjingUniversity,Nanjing210093)LuJianhua　YuJingzhou　ZhuJianzhong　ZhangXiaochun　WangGuilin　ChenJun　WangHongli(YangtzePetrochemicalCo.,Ltd.,Nanjing210048)Abstract　Notonlythevariousbiologicaltoxicityofterephthalicacid(TA)anditswastewaterbutalsotherela-tivetreatmenttechniqueforcontrolthetoxicitiesarereviewedinthispaper,whichisvitaltostudyanddeveloptheef-ficienttechniquesofTAwastewatertreatment,andisveryrealistictomaintainpublichealthandecologicalsafety.Keywords　terephthalicacid;acutetoxicity;sub-acutetoxicity;moleculartoxicity;integrationeffect;toxicitycontrol:“863”(2001AA214191):2003-01-31;:2003-04-14:(1978～),,,:。＊1　TA(terephthalicacid,TA),、、、。TAPTA(purifiedterephthalicacid)。TA30%。TA1,25℃0.0019%,、、。,402℃,166.13,1.5g/mL,。TA,。TA、、;,;。TA。TA,。TA、、、、、、。TA,,。TA,TA。,TA。,,412Vol.4,No.12200312TechniquesandEquipmentforEnvironmentalPollutionControlDec.2003,TA。TA,TA。2　TATA:TA、。、,[1]。TATA。TA,8h,TA13.4%,24h,TA[1]。TA,。1　TATable1　TheacutetoxicityofTA　124hEC50(50%TA,24h)584.33mg/L[6]248hEC50(50%TA,48h)573.32mg/L[6]348hLC50(50%TA,48h)3165.2mg/L[7]496hLC50(50%TA,96h)1111.7mg/L[7]596hLC50(50%TA,96h)6261.1mg/L[8]6LD50(50%TA,)5000—6400mg/kg[2]7LD50(50%TA,)800—1430mg/kg[2]8LD50(50%TA,)15000mg/kg[9]9LD50(50%TA,)1600mg/kg[9]:TA2h,,TA49.35%;,22.67%9.77%。TA2.43—3.4h[2]。TA,TA。TA,TA,[3]。:[4]100mg/LTA,,TA51%,2.16h,TA16.3%。24h50%TA。TA2。TA,30%;TA,[5]。TA1h;TA1.8h。TA。TA[5]。3　TA3.1　,24h。、、。50%。1TA,TA。1,TA、、、、。TA、、。,。TA612—1192mg/L[10],,4d,(1)。,。,。TA。3.2　,712:2　TATable2　ThesubacutetoxicityofTA　　　　　　　　　190d0.5%TA20%[11]290d0.5%TA10%[11]390d5%TA20%[11]490d5%TA90%[11]590d5%TA0%[11]690d5%TA20%[11]790d5%TA10%[13]890d5%TA40%[13]928d64—256mg/LTA62.9%—75.3%[14]1028d32—256mg/LTA37.8%—78.1%[14]3　TATable3　ThemoleculartoxicityofTA　1SD90d20mg/kg·d[15]2SD90d1.0%[16]3SD90d5000mg/kgNAG、ALP[17]4SD90d5000mg/kgα1-MG[17]5SD90d5000mg/kgAST[17]6SD90d,4h/d191.16—340.72mg/m3ACP[18]7SD90d,4h/d191.16—340.72mg/m3NAG[18]8WT90d20mg/kg·d[19]9SD90d5000mg/kg24%[17]1012—24mTA[20]11TA1.0mmol/kg[21]12TA1.0mmol/kg24h[21]13WT5mg/kg·dDNA[22]141.0mmol/kg·dDNA[23]1/10。,、、、。2,TA0.5%—5%,。:(1);(2);(3);(4)TAsprague_daw-ley(SD)wistar(WT)。32—256mg/LTA[11—14]。3.3　DNA、、、、。,。、、。844　TATable4　TAdamagingrespiratorysystem　1TASACE、[25]2TA、[26]3TA8.02mg/m3,6.2,52、[27]4TATA、[28]5　TATable5　IntegrationeffectsbetweenTAandothercompounds　1[25]2、[8]3、[7]4、[8]5、[24]6[29]7[29]8[29]9[30]10、[30]11Na2CO3[31]12[13]　　3,TA7。(NAG),TA,NAG[24]。39—14,TA,,,24%SD。、、,TA,,,,。NOEC(noobservedeffectivecon-centration),(biomark-er),。3.4　TA,TA,4。1—75μm,10μm,,。4,TATA,TA,、、、。TA、,。TA8.02mg/m3。4　TATA,,TA5。(1):TA,。TA:、、、、TA。912:6　TATable6　ThetreatmenttechniquesofTAwastewaterandthespecificdegradationrates(h-1)[32]1996A/O0.0089[32]1996A/O0.0075[10]1997UASB0.0125[33]1991UASB0.0583[33]1991UASBA/O0.0304[34]1992UASB0.0121[34]1992DFF0.0038[35]1993UASB0.0458[35]1993UASB0.0167[36]1997UASB0.0083　　(2):TA,。TA:、、。(3):TA,。TANa2CO3。5,TA,、、、TA,,TA。,TATA,TA,TA。,TA、、,,。5　TATA6。6,TA10,(UASB)6。q()=/(·)。UASBq100.0583h-1,6UASBq0.0121h-1。UASB,q5。,TA,。TA,,TA。TA,。TA,TA,。,,4:(1),,,TA,;(2)、、,TA,;(3)、、,TA,;(4)、、,TA,,。[1]AkioH.,KazuoK.Absorptionofterephthalicacidfromgas-trointestinaltractanddetectionofitsmetabolites.Chem.Pharm.Bull.,1967,15(12):1979—1984[2]AkioH.,KazuoK.Distributionofterephthalicaidintissues.Chem.Pharm.Bull.,1968,16(9):1655—1660[3],..,1997,24(4):223—226[4],..,2001,30(1):26—27104[5]MoffittJ.R.,ClaryJ.J.,LewisT.R.Absorption,distributionandexcretionofterephthalicacidanddimethylterephthalate.Am.Ind.Hyg.Assoc.,1975,36:633—641[6],,,.、、.,2000,7(2):82—85[7],,,..,2000,7(11):78—81[8],,.、、、.,2001,8(1):73—76[9]ChinT.Y.ChemicalurolithiasisbladderstoneinducedbyterephthalicacidanddimethylterephalateinweanlingFischer_344rats.Toxicol.Appl.Pharmacol.,1981,58:307—312[10]ChengS.S.,HoC.Y.,WuJ.H.PilotstudyofUASBpro-cesstreatingPTAmanufacturingwastewater.Wat.Sci.Tech.,1997,36(6—7):78—79[11],,,..,1999,10(3):8—9[12]..,1987,(3):1—3[13]CIIT(ChemicalIndustryInstituteofToxicology).Personalex-posuremonitoring.NC:ResearchTrianglePark,1982[14],.(Daphniamagna).,1998,18(2):117—120[15]HallI.H.,ChapmanJ.M.,GilbertC.Thehypolipidemicactivityofbenzenetricarboxylicacidsinrodents.Pharma.Res.,1984,1(2):63—68[16]BarberE.D.Subchronic90daysoraltoxicityofdiethylhexylterephthalate(DEHT)intherat.Fd.Chem.Toxic.,1995,33(11):971—978[17]..,2002,31(1):10—12[18],,.BALF.,2000,16(11):997—998[19]MeyerB.R.Increaseurinaryenzymeexcretioninworksex-posedtonephrotoxicchemicals.Am.J.Med.,1984,76:989—1001[20]McBeeK.,BickHamJ.W.Petrochemical_relatedDNAdam-ageinwildrodentsdetectedbyflowcytometry.Bull.Envi-ron.Contam.Toxicol.,1988,40:343—349[21]GoncharovaR.I.Astudyonteratogenicityofdimethyltereph-thalate.Genetika.,1988,24(7):1226—1233[22]BartosiewiczM.,TrounatieM.,BarkerD.Developmentofatoxicologicalgenearrayandquantit