降钙素原在新生儿感染性疾病诊断中的应用

:100122087(2004)0120067202:Q573:A,(,200040):(procalcitonin,PCT),140PCT,9,C2(CRP)140PCT99,70.71%;120CRP,30,25%(P0.01)PCT,:;;C2;;:,,1968,,,(procalcitonin,PCT),,PCT[1,2],PCT140,82,58,19.6d,:47;37;22;6;5;4;4;312(,BRAHMSDiagnosticaGmbH),PCTPCT,,PCT,(PCT2PCT2PCT)PCT0.5g/L,,PCT:1ml,200l,30min,,PCT0.50.5210g/L3dPCT0.5g/LPCTC2(CRP),OrionDiagnostica,CRP8mg/L140PCT,99,41,70.71%(99/140),11PCT0.5g/L(g/L)0.521047181512237914212226664522014000431110401306140112470114041502425762004191LaboratoryMedicine2004,Vol19.No1.©1995-2004TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.12PCT(10g/L),CRP2PCTPCT,292,45,16,PCT0.5210g/L,,PCT,PCT0.5g/L212PCT10g/LCRP(d)CRP(mg/L)WBC(109/L)N(%)13815.27128812.78231012512.86441014.412.874512205.767615814.9747151320.367821810.57492816211.37810285711.557112988.654123088.184:WBC,N99PCT,87CRP,27;41PCT,33CRP,3,140,CRP30(27+3),25.0%(30/120)PCT70.71%(99/140),(P0.01)1993Assicot[3]PCT,PCT,[4,5]PCT,,PCT,,PCT(0.5g/L)[1,5]140,PCT99,70.71%,Lorrot[6]PCT78%,CRP,CRP[7],PCTCRP[8]CRP25%,1250%,PCTPCT,,PCT,[1]FerriereF.Procalcitonin,anewmarkerforbacterialinfections[J].AnnBiolClin(Paris),2000,58:49259.[2]GendrelD,AssicotM,RaymondJ,etal.Procalcitoninasamarkerfortheearlydiagnosisofneonatalinfection[J].Pediatr,1996,128:5702573.[3]AssicotM,GendrelD,CarsinH,etal.Highserumprocalcitoninconcentrationinpatientswithsepsisandinfection[J].Lancet,1993,341:5152518.[4]HausfaterP,GarricS,AyedS,etal.Usefulnessofprocalcitoninasamarkerofsystemicinfectioninemer2gencydepartmentpatients:aprospectivestudy[J].ClinInfectDis,2002,34:8952901.[5]VanLeeuwenHJ,VoorbijHAM.Procalcitoninconcen2trationsinthediagnosisofacuteinflammatoryreactions[J].NedTijdschrGeneeskd,2002,146:55259.[6]LorrotM,MoulinF,CosteJ,etal.Procalcitonininpediatricemergencies:ComparisonwithC2reactivepro2tein,interleukin26andinterferonalphainthedifferenti2ationbetweenbactericalandviralinfections[J].PresseMed,2000,29:1282134.[7],,,.C2[J].,2000,15:1242126.[8]HatherillM,TibbySM,SykesK,etal.Diagnositicmarkersofinfection:ComparisonofprocalcitoninwithC2reactiveproteinandleucocytecount[J].ArchDisChild,1999,81:4172421.(:2002212223)(:)862004191LaboratoryMedicine2004,Vol19.No1.©1995-2004TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.