伤速康涂膜液治疗急性软组织

1211(1.410007;2.2000)::,:,,,::R685;R686:A:1005-0205(2003)02-0014-06TheExperimentalandClinicalStudyinTreatingAcuteSoftTissueInjuryWithFast-recoveryInjuryLiquidMembraneLuMen,Fengzhe,YaoGonghe,etalThe1stHosPitalAttachedtoHuNanChineseMedicineCollegeABSTRACTObjective:ToevaluateFast-recoveryinjuryliquidmembraneforactutesoftcontusion.Meth2ods:Weexperimentedonerpeimenalanimalswithantiinflamation,analgesia,acutetoxicityandthetreatmentofacutesofttissueinjurycontusionmodel.Results:OurexperimentshowedthatthenewtypepreparationmadebypureChinesemedicialherbshasantiinflamation,analgesia,noacutetoxicityandtreamentofacutesofttissueinjurytosomeextent.Conclusion:Fast-recveryinjuryliquidmembraneisanewtypepreparationofpaint,madebyXiaoYan-shanthrouthPercolationwithethanolandadedhighmoleculechemicalco2Pounds,webelievedthatthePreParationisagoodexternaldrugfortreatmentofacuteSofttissueContusion.KEYWORDSFast-recoveryinjuryliquidmembraneAntiinflamationanalgesiaAcuteSofttissueContusion,,,,,,,:2003-01-21:,:98324:(1962-),(),,,,,,,,,1285%48,85%41ChineseJTradMedTraum&Orthop,April2003,Vol11,No.2-8020655721,,100ml3,,,,0.5%4:(1)(),754()3000r()()5NIH11.1202gNIH40,4,100.03mlö,15min,30min,6mm,,=(-)ö100%1,t,,(P0.01),,(P0.01),1(xqs,n=10)(%)tP1.3320.110923.9331.5240.205612.93.680.0131.6160.16277.76.460.011.7500.115411.670.01:t3=3.04,P0.01,t33=3.34,P0.011.240202gNIH,4;1h,0.5%0.1mlö10g,0.6%HAC8mlö,,5ml,3000r15min590nm,2t,(P0.01);(P0.01),,,2(xqs,n=10)(xqs)tP0.13080.0051330.13550.00552.760.0530.13920.005484.990.010.14610.00489.940.01:t3=4.24,P0.01,t33=6.49,P0.011.340,150190g,4,10,1%0.1mlö30,,6h0.5cm,5ml1h,,,0.1ml0.5molöLKOH-2ml754E2(PGE2),PGE23t,(P0.01),;,PGE2,,22.1NIH202g404,,30min51200341120.7%0.2mlö,(,)20min,4t,(P0.05,0.01),,31%PGE2(xqs,n=10)PGE2xqstP0.109580.00047330.109940.000352.750.0530.110210.000424.250.010.110870.000399.420.01:t3=5.13,P0.01,t33=7.89,P0.014(xqs,n=10)tPö20min%tP7.20.320.13.531.6336.90.302.520.0524.13.718.03.540.0136.10.49.370.0124.43.217.04.0660.015.90.29.840.0129.43.18.880.01:t3=4.98,P0.01,t33=4.92,P0.012.2202gNIN40,4,,,1cm,,,5,,0.5mA24h48h,567t,(P0.05P0.01),,55(xqs,n=10)xqstP0.90930.0189330.89760.01272.290.0530.88570.00835.110.010.88010.00966.150.01:t3=1.97,P0.05,t33=4.91,P0.01624(xqs,n=10)xqstP0.71540.0159330.70560.012072.2220.0530.69660.012864.160.010.68480.009057.590.01:t3=6.16,P0.01,t33=3.35,P0.013300400g36,,3:,,1200g10cm,20,21cm2,1,,,;,2,2468,3,,3.10:1:,,2:,,,3:,,748(xqs,n=10)xqstP0.37720.01330.36910.01012.530.0530.36440.009074.210.010.36140.01024.660.01:t3=0.99,P0.05,t33=2.40,P0.053.28V291061ChineseJTradMedTraum&Orthop,April2003,Vol11,No.283441129210120011112912012111121311:V2=126.3,P0.011011112111121212:V2=54.55,P0.0111(n)R113440.63251129210.37871910,Ridit11,0.59060.67440.33680.4206,,,:,,2,46,8,:3,;46,(),8,4250300g4()22cm,,,,,,3,,:,55,4,()24h,,1510cm2,,0.68gög,0.34gög,2g,,,24h,1h,,,1212(xqs,n=4)2.190.342.180.22.250.372.180.242.170.322.200.202.162.222.200.372.100.202.170.312.210.282.180.182.200.372.170.222.160.32.230.262.180.192.220.402.170.202.170.332.230.242.210.172.200.362.150.222.150.362.250.272.200.152.240.332.170.212.170.352.230.252.240.182.310.342.220.242.270.24P0.05,60kgkg416213,,,,:71200341121,(P0.05P0.01)23451,:,,:,,,;,,,,,?:,,,,,,,2:,,,:,,,,,,,,,,1,,46,,14,,,,,2:,,,,3,,,,4(P0.010.05),5(P0.05),6(P0.01),7,PGE2,-MDA,,,:(1),,,,,,(2),,,,3,,,,,,81ChineseJTradMedTraum&Orthop,April2003,Vol11,No.2,8,9,,,,,,,,:;,,1..,1995,3(5)2..,1997,85(4)3..,1999,7:122(4)4..,1990;12(1):305..,1991,13(4):306..,1990,12(7):297..,1992,14(4):328.20.,1984,4(9):5559..,1986;11(7):541.,,5,16,,,1700,30,,,20028,:360,,,,:856,,:4300742.,16,,4,,,,385,,,,,,45,,35(),,:856,,:4300749120034112©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.