带状疱疹后神经痛诊疗中国专家共识(pdf版)

(postherpeticneuralgia,PHN)(HerpesZoster,HZ)1PHNPHNPHN3.942.0/10359%34%PHNPHN6065%PHN7075%400PHNPHN1-(Varicella-ZosterVirusVZV)PHNPHN2-(spontaneouspain)(hyperalgesia)(allodynia)AAPHN-(differentiation)1.50%10%20%2%8%1%PHN30%50%1102.PHN45%60%40%--PHN21PHN---------------------------------------------------------------------------------PHNPHNPHNPHN---------------------------------------------------------------------------------(VAS)(NRS)ID-PainDN4PainDETECTMcGill(MPQ)McGill(SF-MPQ)SF-36Nottingham(NottinghamHealthProfileNHP)(QoL)2PHN---------------------------------------------------------------------------------1.2.3.PHNTzanck---------------------------------------------------------------------------------PHNPHNPHN21VASNRS30%50%PHN1.2010(EuropeanFederationofNeurologicalSocieties,EFNS)2004(AmericanAcademyofNeurology,AAN)PHN2015(InternationalAssociationfortheStudyofPain,IASP)(NeuPSIG)PHN5%PHN1(VGCC)2-300mg9003600mg20%30%2-PHN150600mg5790%10%15%2(TCAs)5-12.525mg150mg3PHN(4h)4121/41/350%PHN4-/5-PHN2550mg12400mg5-SNRIs5-5PHNPHN81265-(SNRIs)PHN150225mg13060mg12PHN44.0Neurotropin/20.025%0.1%50400mg12200400mg22501000mg30.4mg32.PHNPHNPHN11%1/3002PHN2Hz45V20ms480msATPC(SpinalCordStimulation,SCS)(PeripheralNerveStimulation,PNS)(TranscutaneousElectricalNerveStimulation,ENS)SCSSCSPHN13PNSTENS3.5PHNPHN2016.223