无痛人流术中异丙酚伍用氟比洛芬酯的疗效和安全性

©1994-2010ChinaAcademicJournalElectronicPublishingHouse.Allrightsreserved.(p0105),,,,AbstractObjectiveTostudytheeffectsofintravenousPropofolcombinedwithFlurbiprofenaxetilonpainlessartificialabortion.Methods60Patientsscheduledforartificialabortionwithpregnancywererandomlyallo2catedintotwogroups:Propofolgroup(groupP,n=30),PropofolcombinedwithFlurbiprofenaxetilgroup(groupP+F,n=30).Theanalgesiceffect,cervicalrelaxationandartificialabortionsyndromewererecordedattheperform2ance.ResultsThescoresoftheanalgesiceffect,cervicalrelaxationingroupP+Fwere90.0%and93.3%,whichweremuchhigherthanthoseof3010%and46.7%ingroupP,respectively,p0.05.Duringthepainlessar2tificialabortion,comparedwithgroupP,theincidenceofartificialabortionsyndromeingroupP+Fwas6.6%,whichwassignificantlylowerthanthatingroupP,p0.05.ConclusionIntravenousPropofolcombinedwithFlur2biprofenaxetilwasasafeandeffectivemethodonartificialabortion,itcouldobviouslyreducetheincidenceofartifi2cialabortionsyndrome.KeywordsPropofol,Flurbiprofenaxetil,Painlessness,ArtificialabortionAuthorsaddressAnesthesiologyDepartmentofTheFirstAffiliatedHospital,SunYet-senUniversityofMedicalSciences,Guangzhou,GuangdongProvince510080PRC,,,(artificialabortion:510080syndrome)[1-2],11.160,ASA()[3].200[J].,1999,13(3):64.[4].40[J].,1999,19(6):59.[5],.[J].,1999,27(1):56.[6].[M].2.:,1991:525.[7]FERREIRAS.PROSTAGLANDISH.themechanismofanalgesicproducedbyaspirin-likedrug[J].AnnRevPharmae,1974,14:5.332008810ModernHospital2008Vol8No10©1994-2010ChinaAcademicJournalElectronicPublishingHouse.Allrightsreserved.(BP)(HR)(SpO2),,2mg/kg,15min1mg/kg2mg/kg1.3:WHO,0:;():,;():;():,:():,67;():6767;():,47:[2]1.4(xs),SPSS1010,t,222.1(p0105),(p0105)(12)1(xs,n=30)(y)(kg)(min)25.46.751.810.44.71.426.27.053.210.65.11.7:,p0.052(xs,n=30)3minMAP(kPa)11.12.39.31.310.31.210.72.19.61.510.21.1HR(min-1)85.810.178.77.674.37.788.211.982.28.577.68.3SpO2(%)98.30.595.51.796.61.697.20.695.31.697.01.4:,p0.052.2024,3,2,1,09010%;03,16,18,6010%,3,1010%,03010%p0105,2.317,11,2,9313%;8,6,16,4617%,p0105,2.42/30(616%),9/30(3010%),p0105,3,[1],,[3],2mg/kg,,,,,,,510min,[4-5],,,9010%,3010%;9314%,4617%;313%,2617%,p0105,,,,,,,,,,,,,[1],,.[J].,2002,18(11):615.[2],.[M].:,1988:223.[3],,,.[J].:,2004,25(3):283-284.[4]OCHROCHEA,MARDINIIA,GOTTSCHALKA.WhatistheroleofNSAIDsinpre-emptiveanalgesia?[J].Drugs,2003,63(24):2709-2723.[5]UEKIR,TANIMOTOM,TATARAT,etal.Emulsionofflurbi2profenaxetilreducespropofolinjectionpainduetoadecreaseinfreepropofolconcentration[J].JAnesth,2007,21(3):325-329.432008810ModernHospital2008Vol8No10