铁的生物学功能与代谢调节研究现状

[18],2.3,[19](120g),3,34,[20]()51,,2.4,,,,[21]0.5mL,,216,76%,[22]31,2mL,bid,()6d,,,2.5,(tietzesdisease)3,,,,,[][1],,,.[J].,2003,15(1):18-19.[2],,,.[J].,2000,21(3):204-206.[3],,,.[J].,2003,25(3):125-126.[4],,.[J].,2004,38(4):333-335.[5],,,.()[J].,2004,2(4):195-198.[6],,,.TNFNO[J].,2003,34(2):152-154.[7],,,.moesinmRNA[J].,2002,22(10):579-581.[8],,,.DICLPOSOD[J].,2004,23(1):4-5.[9],,.[J].(),2003,22(3):25-27.[10],,,.F022[J].,2002,27(6):439-441.[11],.[J].,2000,19(4):53-54.[12],,,.[J].,2003,23(6):327-329.[13]WangZM,ZhuXX,CuiXL,etal.ScreeningoftraditionalChineseremediesforSARSTreatment[J].ChinaJChineseMateriaMedica,2003,28(6):484-487.[14],,,.[J].,1988,13(2):31-32.[15],,SorenBC,.[J].,2001,17(6):714-715.[16],,.[J].,2000,23(6):559-562.[17].30[J].,2004,10(4):28-29.[18],.[J].,1995,(1):24.[19],,.[J].,2003,11(6):63.[20].51[J].,2004,13(6):732-733.[21].[J].,2003,21(3):232-233.[22].31[J].,2004,4(17):961-962.1,2,1(1.,317000;2.,318000)[],,,[];;;[]R977.5[]A[]100420781(2005)1020922203229HeraldofMedicineVol124No110October2005©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,,WHO,,(IDA)1/3IDA,4,WHO[1,2],1,(,,,),,,,1.1,60%70%,,,,,,,IDA[3],50%IDA20%88%,IDA36%45%20%IDA[4]1.2:,;,,,,,,,,,,,[5]1.3,T,4;B;;,,[6][]2005204204[]2005205218[](1967-),,,,:(0)13957689898,E2mail:[e-mail]1.4,,,Beard[7],,,(FT3)(FT4)1.5,,,,,,,,,,,,,[3];,,[8];,,,1.6[9]DNA,,p53,GADD45,WA1/p21,,1.7UCP2,3,mRNA,,[3];,;IDA2(TfR),[10](Tf)2(TfR),TfTfR,Tf2,,,Tf,,TfTf2TfRs2TfR/sFs2TfRTfRTfR,sF,IDAs2TfR/sF[10,11],3292005102410©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,,(ARDS)[12],T,[13],,p53,GADD45,UAF1/p21,,,[14],[15](ACD)[16]ACD,IDAACD,Tf,Feton,,,,,,,33.1A(VitA),VitAVitAVitAIDA,VitA,VitAIDAVitAVitAVitA,VitA,,[4,17]3.2,,,,,,,,,[18]3.3(VitC)(EDTA),VitCEDTA[19]Davidsson[20],(VitCEDTA),EDTA,,VitC,4,,,,,,[][1]WorldHealthOrganization.Malnutrition,TheGlobolPicture[M].Geneva:WorldHealthOrganization,2000.57-59.[2].[J].,2005,32(1):42-46.[3].X[J].,2003,24(2):74-75.[4].A[J].,2003,30(3):155-158.[5].[J].,2002,10(3):220-224.[6],.A[J].,2001,23(1):36-38.[7]BeardJ,BorelMJ,PetersonFJ.Changeinironstatusduringweightlosswithvery$low2energydiets[J].AmJClinNutr,1997,66(1):104-110.[8],.[J].,2001,32(1):22-23.[9],.[J].,2002,7(1):6-7.[10],.[J].,2003,26(3):247-249.[11].[J].,2002,7(1):41-44.[12].[J].,2003,24(3):132-134.[13].[J].,2003,24(4):148-151.[14].[J].,2002,25(4):342-344.[15],.[J].,2002,25(2):151-159.[16].[J].,2003,8(4):186-188.[17].A[J].,2003,30(5):287-291.[18]LeahHZ,SandraR,DavisK,etal.Afungalmulticopperoxidaserestoresironhomeostasisinaceruloplasminemia[J].Blood,2004,103(23)4672-4673.[19].EDTA[J].,2003,24(1):26-27.[20]DavidssonL,WalezykT,IavaletaN,etal.ImprovingironabsorptionfromaPeruvianschoolbreakfastmealbyaddingascorbicacidorNa22EDTA[J].AmJClinNutr,2001,73(2):283-287.429HeraldofMedicineVol124No110October2005©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.