研究生复试、小组会ppt英文模板

PTR-MS&QuadrupoleionguideOutlinePTR-MSQuadrupoleionguideNextworkPTR-MSIntroductionOverviewDevelopmentApplicationComponentIonSourceDriftTubeQuadrupolemassanalyzer？？？PTR-MS李建权等.质子转移反应质谱的建立与性能研究[J].分析化学,2008,36(1)细胞检测器ATP质谱图OverviewPTR-MSDevelopment1966:F.H.FieldandM.S.B.Munsondevelopedchemicalionization;1969:Flowingafterglowandflowdrifttubetechnique(FDT)developedbyFergusonandcolleagues;1990s:OnthebasisofSIFT-MS,Innsbruke’sLindingerteamputforwardthePTR-MStechnologyforthefirsttimeincombinationwithchemicalionizationtheory(1996)anddrifttubemodel(1969).InJuneof1995,Lindinger:Acetonitrileandbenzeneinthebreathofsmokersandnon-smokersinvestigatedbyPTR-MS;InJulyof1995,Lindinger:PTR-MS:OnlineTraceGasAnalysisatppbLevel.1998,thefirstcommercialPTR-MSinstrumentwasproducedbyIONICONAnalytik.SchematicofPTR-TOF-MSBlakeRS,WhyteC,HughesCO,etal.Demonstrationofproton-transferreactiontime-of-flightmassspectrometryforreal-timeanalysisoftracevolatileorganiccompounds.[J].AnalyticalChemistry,2004,76(13):3841-5.HanselA,etal.Proton-transfer-reactionmassspectrometry(PTR-MS):on-linemonitoringofvolatileorganiccompoundsatvolumemixingratiosofafewpptv[J].PlasmaSourcesScience&Technology,1999,volume8(2):332-336(5).SchematicofPTR-MSPTR-MSDevelopmentHighsensitivity(afewpptv)MultichanneldataacquisitionApplicationsAirqualitytesting(Real-timeonlinequantitativemeasurementsoftraceVOCs)Biologicalresearch(Monitortheresponseofplantleafwounds)Foodscienceandaromaindustry(Researchonaroma,Productionprocesscontrol)Diseasediagnosis(Lungcancer,Rectalcancer,diabetes)PTR-MS…IonSource(H3O+Generator)伍小梅等.在线检测挥发性有机物的质子转移反应飞行时间质谱仪的研制[J].质谱学报,2015,36(1)StructureofDoubleHollowCathodeDischargeDriftTube(Protontransferreaction)StructureofDriftTube李建权,沈成银,王鸿梅等.质子转移反应质谱的建立与性能研究[J].分析化学,2008,36(1)32[]VOCsHOVOCsHHOQuadrupolemassanalyzera.Hyperboloidb.Cylinder有效区域四极场作用区域Machiningdifficulty：abMachiningaccuracy：baFreedegree：r/r0r=1.148r0(Deviation1%)直流分量:u交流分量:Vcosωt场半径:r0令ξ=1/2ωtMathieu方程Quadrupolemassanalyzer方向,覃莉莉,白岗等.四极杆质量分析器的研究现状及进展[J].质谱学报,2005,26(4)Mathieu参数QuadrupolemassanalyzerStabilityofSolutionofMathieuEquationQualityscanline:y=kx(k=a/q=2U/V)ChangingthevaluesofUandVcanachievequalityscanning.ThemovementofionsinthequadrupolecanbedescribedbythesolutionoftheMathieuequation.Firststableregion方向,覃莉莉,白岗等.四极杆质量分析器的研究现状及进展[J].质谱学报,2005,26(4)QuadrupolemassanalyzerMillerPE.InvestigationsoftheRF-onlyquadrupolemassanalyzer[J].Dissertations&Theses,1985.m+1:passm,m+2:can’tpassm+1,m+2:passm:can’tpassChangingtheslopeofthequalityscanline(K=a/q),thatis,changingtheu/vvaluecausesthescanlinetomovedown.WhatwillhappenifK=0(u=0)?OutlinePTR-MSQuadrupoleionguideNextworkQuadrupoleionguide(RF-onlyionguide)Whydowewanttousequadrupoleionguide?ReducethelossofionsinthetransmissionpathReducethespacedivergenceandenergydispersionofionsImprovesensitivityTransmissionefficiencyishighRequirementofvacuumdegreeislowQuadrupoleionguide(RF-onlyionguide)Whenu=0,themassscanlinecoincideswiththeqaxis,theoretically,alltheionsinthestableregioncanpassthroughthequadrupoleionguidedevice.黄超.基于频率扫描的数字化四极杆滤质器的研究[D].天津大学,2007.2LINAC式1.Guo,etal.Aradiofrequencysignaldriverforquadrupoleusedindesktoporthogonal-injectiontime-of-flightmassspectrometer☆[J].NuclearInstruments&MethodsinPhysicsResearch,2012,694(6):255-262.2.3.4.黄正旭.高分辨垂直引入式飞行时间质谱仪原理及设计.[D].广州.中科院广州地球化学研究所，2009134Quadrupoleionguide(RF-onlyionguide)Quadrupoleionguide(RF-onlyionguide)ProbulemsmustbesolvedWorkingairpressureofquadrupoleionguide-designofthevacuumsystem(selectionofpump,Cavitysize,openingsize...)ParameterestimationandmechanicaldesignofQuadrupoleDesignofmatchingcircuitLow-masscut-offvalue(LMCO)TestandmodifyOutlinePTR-MSQuadrupoleionguideNextworkNextworkLearnhowtouseSIMIONDefinetheenergy,angle,andpositionofrandomionsDefinetheparametersofthequadrupoletransmission(voltage,physicaldimension...)NextworkLearntobuildtestplatformParameterestimationofRFQRefinecurrentdesignandtestplatformLearnhowtomatchelectriccircuits…CooperationProgressAjourneyofathousandmilesbeginswithasinglestepTHANKS!