新型快速血糖仪监测血糖的可靠性评价及其社会意义

,430022108(CBG),(VSG):,2,VSGCBG(210710135)%,CBGVSGVSG611,CBGVSG,,r01850189,P0105CV,96124%ABCBG,,,;;;R71918AEvaluationoftheReliabilityofNewlyDevelopedBloodGlucoseMeteranditsSocialValueZhouMinetalDepartmentofEndocrinology,XieheHospital,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan430022AbstractCapillarybloodglucose(CBG)of108diabetespatientsweremeasuredbyGlucotrendbloodglucosemeter,andvenousserumglucose(VSG)ofthesamepatientsweremeasuredaswellbyoxygenationmethodascontrol.ComparisonstudyshowedtherewasnosignificantdifferencebetweenCBGandVSGonthewhole,andVSGwashigher2107%thanCBG,thecorrelationbetweenthosetwomethodswassignificant.Amongthe5sub2groups,whenVSGlevels611mmol/L,CBGshowedeitherhigheroflowerthanVSG;whenVSG611mmol/L,CBGshowedeitherhigherorlowerthanVSG;whenVSG611mmol/L,CBGatalllevelwaslowerthanVSG(P0105),andrvaluewasbetween0185to0189(P0105).ReliabiltytestofthebloodshowedalowCVvalueandhighaccuracy.ErrorTableanalysisdemonstrated96124%ofthedatawereintheacceptableAandB.Wecouldconcludethatasaclinicalmethod,CBGmonitoringbynovelbloodglucosemeterwassim2ple,quick,precise,reliableandneedverysmallamountblood.Itsofhighclinicalreliabilityandeasytobeacceptedbythepatients,andalsothesocialvalueofthistechnologyisremarkable.Keywordsbloodglucosemeter;capillarywholebloodglucose;venousserumglucose;self2moni2toringofbloodglucose(DCCT)(UKPDS),,,4[1],,,,,,RocheGlucotrend,(CapillaryWholeBloodGlucose,CBG)(VenousSerumGlucose,VSG),1111,1082112RocheGlucotrend:2216320036MedicineandSocietyVol116No13Jun12003(,20010101)113(1):,212ml,2h(2):Roche(318516mmol/l,9101119mmol/l),10,(3)2l5l10l20l,(4)1015253540,114VSG5,611,611-1111,1111-1616,1616-20,20(mmol/L)115…xs,t,(r),t(EGA)Clarke[2]SAS61122211CBGVSG,1212,108CBG141006156VSG141156144,,(r)0198,P0101,;,VSG611mmol/lVSGCBG,r01850189,;VSG611mmol/l,VSGCBG(P0105),(r=0168)212241660112101480134,CV1176%2175%,2132lErr,5l10l20l30l(P0105)1015253540(P0105)214A91102%B5122%C2161%D1115%1CBGVSGNCBG(mmol/l)VSG(mmol/l)VSG2CBG(mmol/l)VSG2CBG(%)3611611-11111111-16111616-20201081129331817141005155817414102171982419161560177117811782132318614115513681321317418120251116144014611371148110041240115-011801430128012201201121015711061118118101982107-312711182115213931519187101351214481591010241553(VSG-CBG)/VSG100%;VSG:P0105;:P010522NrP611611-11111111-16161616-20201081129331817y=0196x+0167y=1114x-0156y=1104x-0108y=0191x+1156y=0189x+3129y=0182x+61640198270168000180280185350189800187480101010101010101010101013311Glucotrend108,,2VSG611mmol/lVSG20mmol/l,,,CV,,VSG96124%AB,321[1],,CBGVSG[3,4],,111112110207,,,(17%79%)[5],,,,30%,[6],,3l,Glucotrend,,,:,,,3l1040,,312,,,[7]20701%,215%,1%,5%3[8],WHO,20253[9],,(self2monitoringofbloodglucose,SMBG)10,,,,[1,9],,,,,,,,,,,,,,5%[8],34[10],21,,,,[1]AmericanDiabetesAssociation:Consensusstatementofself2monitoringofbloodglucose[J].DiabetesCare,1987,10:95[2]ClarkeWLetal.Evaluatingclinicalaccuracyofsystemsforself2monitoringofbloodglucose[J].DiabetesCare,1987,10:622[3]1[M]1:,19971276[4],1[J]1,1999,20(7):531532[5]VelazquezFR.BartholomewD.Effectofsmallsamplevol2umeonfiveglucosemonitoringsystems[J].DiabetesCare,1996,19:903[6]FloraD.OkiJ.FrequencyandimpactofSMBGonglyc2erincontrolinpatientswithNIDDMflowedinspecialtyclinicofaninnercityteachinghospital[J].Diabetes,1996,45:69A[7]AmericanDiabetesAssociation:ImplicationsoftheUnitedKingdomProspectiveDiabetesStudy[J].DiabetesCare,2000,23(suppl1):S27[8]1[M]1:,200111417[9]11[M]1:,20011798811[10]Olefsky,TerroldM.MD.ProspectsforResearchinDia2betesMellitus[J].JAMA,2001,285(5):628632(2003204210)()4220036163