2017V1.CSCO乳腺癌诊疗指南

CSCO2017.V1CSCO2017.V1CSCOCSCOCSCO2017.V1CSCO(2017.V1)2016.04CSCOBC2016.05CSCOBC22016.12CSCOBC2017.01.07CSCOBCCSCO2017.03.072017.04.07CSCOBC2017.04.09CSCOBC2017.04.22CSCOCSCO2017.V12017.01.07CSCOBCCSCO2017.V12017.01.07CSCO2017.V1CSCOBC2017.03.07CSCOBC2016.12CSCOBC2016.05CSCO.CSCOBC2017.01.07CSCOBC2017.04.09CSCOBC2017.04.072017CSCOBCCSCOBCCSCO.2016.042017.04.22CSCOCSCO2017.V1OCSCO2017.V1CSCO2017.V1CSCO2017.V1CSCO2017.V1CSCO2017.V1CSCO(2017.V1)CSCO2017.V1HER-2CSCO2017.V11.2.ERPRHER2Ki673.1.2.3.4.5.CSCO2017.V11(AmericanJointCommitteeonCancer,AJCC)7AJCC234CSCO2017.V11.5cm2.3.HER-24.5.1.3cm2.HER-2cmCSCO2017.V11.2.A3.T4.ATTACAC-T1.BRCA/TP2.AT4NPCSCO2017.V11-3/612BMRIB2MRIRECIST1.13CSCO2017.V14-6/6450mg/m25pCRpCRpCRpCRpCR6pCRCSCO2017.V11HER-2pCR1HER-22pCR3pCR2B4CSCO2017.V11/2AC-TAC-DA60mg/m2d11/21dC600mg/m2d1D80-100mg/m2d11/21dEC-DE90mg/m2d11/21dC600mg/m2d1D80-100mg/m2d11/21dAC-wPA60mg/m2d11/21dC600mg/m2d1P80mg/m2d11/7dEC-wPE90mg/m2d11/21dC600mg/m2d1P80mg/m2d11/7dAC-TCSCO2017.V1ATA60mg/m2d11/21dT75mg/m2d1ETE75mg/m2d11/21dT75mg/m2d1TACCSFT75mg/m2d11/21dA50mg/m2d1C500mg/m2d1AT-NPA60mg/m2d11/21dT75mg/m2d1N25mg/m2d181/21dP75mg/m2d1-3ET-NPE75mg/m2d11/21dT75mg/m2d1N25mg/m2d181/21dP75mg/m2d1-32/2CSCO2017.V1HER-21.5cm2.3.HER-24.5.1.3cm2.HER-2cmCSCO2017.V1HER-21.2.3.TCbH1.TH-ACAC-TH2.FEC-THAC-THCSCO2017.V1HER-2(1-4/7)1HER-2pCRHER-2HER-22434pCR1CSCO2017.V1HER-2(5-7/7)5TH-ACTCbHTH-ACAC-THHER-2AC/EC-TH67HER-2NeospherepCRCSCO2017.V1TH-ACT80mg/m2d11/7dH4mg/kg2mg/kgd1A60mg/m2d11/21dC600mg/m2d1ECH-THE90mg/m2d11/21dC600mg/m2d1H8mg/kg6mg/kgd1T80-100mg/m2d11/21dH6mg/kgd1TCbHT75mg/m2d11/21dCbAUC6d1H4mg/kg2mg/kgd11/7d8mg/kg6mg/kgd11/21dPHTP840mg420mgd11/21dH8mg/kg6mg/kgd1T75mg/m2100mg/m2d1CSCO2017.V1HR15023264CSCO2017.V1CSCO(2017.V1)CSCO2017.V1HER-2HER-2CSCO2017.V11.2.ERPRHER-2Ki-671.21Oncotype1.2.3.4.5.1.2.CSCO2017.V11AmericanJointCommitteeonCancerAJCC7AJCCTNMM23LuminalCSCO2017.V1HER-21.T22.N13.AC-TH1ATCbH2cmTC4HwPHHCSCO2017.V1HER-21.GoldhirschA,etal.Lancet2013;382:102128.2.2.PerezEA,etal.SABCS2012.;3.3.SlamonD,etal.2011HER210DFS(%)10OS(%)HERA151021169.3%24%81%26%NCCTGN9831/NSABPB3122101/35058.473.7%40%84%37%BCIRG0063322210.374.6%28%85.9%37%73%23%83.3%24%CSCO2017.V1HER-21T1c2T1b3T1aKi-67CSCO2017.V1HER-2123HER-21CSCO2017.V11/2AC-PHA60mg/m2d11/21d4C600mg/m2d1P175mg/m2d11/21d480mg/m2d11/7d12H4mg/kg2mg/kgd11/7d18mg/kg6mg/kgd11/21d1AC-DHA60mg/m2d11/21d4C600mg/m2d1D80-100mg/m2d11/21d4H4mg/kg2mg/kgd11/7d18mg/kg6mg/kgd11/21d1EC-PHE90mg/m2d11/21d4C600mg/m2d1P175mg/m2d11/21d480mg/m2d11/7d12H4mg/kg2mg/kgd11/7d18mg/kg6mg/kgd11/21d1EC-DHE90mg/m2d11/21d4C600mg/m2d1D80-100mg/m2d11/21d4H4mg/kg2mg/kgd11/7d18mg/kg6mg/kgd11/21d1CSCO2017.V12/2TCbHT75mg/m2d11/21d6CbAUC6d1H4mg/kg2mg/kgd11/7d18mg/kg6mg/kgd11/21d1TC4HT75mg/m2d11/21d4C600mg/m2d1H4mg/kg2mg/kgd11/7d18mg/kg6mg/kgd11/21d1wPHP80mg/m2d11/7d12H4mg/kg2mg/kgd11/7d18mg/kg6mg/kgd11/21d1CSCO2017.V11.2.3.HER-2T1b4.3cm5.31.2.CSCO2017.V1HER-21.42.133.1.AC-T/31A2.AC-T/1A1.AC-wT1A2.TAC3.FEC-T1.13luminalA2.Ki-67303.24.35AC1ATC1ACSCO2017.V11-6/9123456CSCO2017.V17-9/97T1N0AC-TCALGB9741AC-T8LuminalLuminalA13ACTC4AC9Ki-67HRT1N0Ki-6730Ki-6715Ki-671530CSCO2017.V11/3AC-TAC-DA60mg/m2d11/21d4C600mg/m2d1D80-100mg/m2d11/21d4EC-DE90mg/m2d11/21d4C600mg/m2d1D80-100mg/m2d11/21d4AC-wPA60mg/m2d11/21d4C600mg/m2d1P80mg/m2d11/7d12EC-wPE90mg/m2d11/21d4C600mg/m2d1P80mg/m2d11/7d12CSCO2017.V12/3EC-PCSFE90mg/m2d11/14d4C600mg/m2d1P175mg/m2d11/14d4AC-PCSFA60mg/m2d11/14d4C600mg/m2d1P175mg/m2d11/14d4ACA60mg/m2d11/21d4C600mg/m2d1ECE90mg/m2d11/21d4C600mg/m2d1TCT75mg/m2d11/21d4C600mg/m2d1CSCO2017.V13/3TACCSFT75mg/m2d11/21d6A50mg/m2d1C500mg/m2d1FEC-T5-FUF500mg/m2d11/21d3E100mg/m2d1C500mg/m2d1T80-100mg/m2d11/21d3CSCO2017.V11ERPR2ER19ER193CSCO2017.V16060121FSH60FSHCSCO2017.V1AI5AI55AITAMG3TAM5AICSCO2017.V11MA17R35TAM5AI5AIAI1025AI5TAMAI5AI2-535AIAI5TAM4AI5CSCO2017.V11.2.G13.T2cm4.TAM51.G2-3132.OFSTAM551.TAM52.AI2B1.2.G3OFSAI551.OFSAI5TAM52.AI52BCSCO2017.V11GnRHaGnRHa2OFS3OFSTAMAI42343AIG2132cmTAM5AICSCO2017.V11NSABPB-14ATLASaTTom10TAM5TAMTAM5TAMTAM10G3253TAM5AI5CSCO2017.V1CSCO(2017.V1)CSCO2017.V1HER-2CSCO2017.V11.2.3.4.5.1.2.3.CT4.5.6.7.PET/CTCSCO2017.V11-4/9123ERPRHER-2HER-24CTMRICSCO2017.V15-7/95ECTECTXCTMRI20146CTMRIHER-27PET-CTPER-CTCTMRIPET-CTCSCO2017.V18-9/98RECIST1.191CSCO2017.V11.2.TX3.GT1.2.3.1.2.NX2B3.NP2B4.GPCSCO2017.V111.2.3.CSCO2017.V1PS()AlkenS,KellyCM.CancerManagRes2013;5:357-365.eCollection2013.MBCCSCO2017.V1175mg/m2d11/21d80mg/m2d11/7d75mg/m2d11/21d260mg/m2d11/21d100150mg/m2d18151/28d1000mg/m2bidd1141/21d1000mg/m2d11/7d25mg/m2d11/7d6090mg/m2d11/21d6075mg/m2d11/21dCSCO2017.V1TXT75mg/m2d11/21dX1000mg/m2bidd114NXN25mg/m2d181/21dX1000mg/m2bidd114NPN25mg/m2d181/21dP75mg/m2d13GPG1000mg/m2d181/21dP75mg/m2d13GPG1000mg/m2d181/21dPAUC2d18CSCO2017.V1HER-21.2.3.4.1.2.3.4.HER-21.2.1.2.T-DM1HER2CSCO2017.V11HER-22HER-2CSCO2017.V1PFSOSH0648gPacH++M77001DocH++USOncologyPHvs.PCH+-CHATHTvs.HTX+/CLEOPATRADoc+HP++HER-2CSCO2017.V11HER-22HER-23HER-2HER-2HER-2CSCO2017.V11682HER-2HER-2HER-23HER-2HER-2CSCO2017.V11HER-2HER-2212HER-212HER-23HER-24HER-2HE