药学英语-标准试卷5

试卷（A）共（5）页第（1）页一、翻译（共20分,每题1分）。1Hexane2Mercury3Potassium4Cysteine5Methionine6Amide7Ethylacetate8Potassiumcarbonate9Sodiumbicarbonate10Pentane11苏氨酸12腺苷酸13氯14碘15脯氨酸16色氨酸17酮18环己烷19CaCO320氯化钠答案：1己烷2汞3钾4半胱氨酸5甲硫氨酸6酰胺7乙酸乙酯8碳酸钾9碳酸氢钠10戊烷11Threonine12Adenylicacid13Chlorine14Iodine15Proline16Tryptophan17Acetone18Cyclohexane19Calciumcarbonate20Sodiumchloride二、写出下列缩写的英文全称并翻译（共10分,每题2分）。1QSAR:2TLC:3UV/visible:4MBA:5CEO:答案：1QuantitativeStructure-ActivityRelationship定量构效关系2ThinLayerChromatography薄层层析法试卷（A）共（5）页第（2）页3Ultraviolet-visiblespectroscopy紫外分光光度法4Master(Management)ofBusinessAdministration工商管理硕士5ChiefExecutiveOfficer首席执行官三、判断（共16分,每题2分），并用×√表示。1（）Analyticalchemistsworktoimprovethereliabilityofexistingtechniquestomeetthedemandsforbetterchemicalmeasurementswhichariseconstantlyinoursociety.2（）Aspecificreactionortestisonethatoccuronlywiththesubstanceofinterest.3（）Theleadcompoundisnotintendedtobeusedasaclinicalagent.4（）Biomoleculesarecompoundsofcarbon.5（）Highlypolarwater-solubledrugsbeingtransferredslowlywhereashighlylipidsoluble,non-polardrugsaretransferredrapidlyacrossthelipid-richmembranesofcells.6（）Thedegreeofaqueoussolubilityofthedrugaffectstherateofthedissolution.7（）Directcomparisonwithauthentic(ifavailable)shouldnotbecarriedoutasfinalconfirmation.8（）Leadcompoundscanbeobtainedfromavarietyofdifferentsourcessuchasthefloraandfaunaofthenaturalworld,orsyntheticcompoundsmadeinthelaboratory.ThereisalsothepotentialofdesigningleadcompoundsusingcomputermodelingorNMRspectroscopicstudies.答案:1√2√3√4×5√6√7×8√四、单选题（共14分,每题2分）。1QuantitativeanalysisDwiththedeterminationofhowmuchofoneormoreconstituentsispresent.AdoBresearchCseekDdeal试卷（A）共（5）页第（3）页2Presently,D,itisappliedinaverygeneralmannertosyntheticaswellastonaturalcompoundsinthesearchfornewleadcompound.AUVBNMRCIRDHTS3alcoholshaveoneormoreCgroupsAacetylBaldehydeChydroxylDcarboxyl4Cviewofthecomplexityofthehumanbody,itisinevitablethatpharmacokineticformulationsmustbebasedondrasticallysimplifyingassumptions.AInBAtCByDAs5Athetemperatureismaintainedataconstant37℃,andtheagitationofstirringrateisheldtoaspecifiedconstant.AInvivoBInvitroCInaqueoussolutionDInvacuum6InUVAofthematerialarerequired,sincethestandardspectrophotometriccellonlyhold3mLofsolutionand,usingspecialcells,onlyonetenthofthisvolumeneedbeavailableforspectrophotometry.AonlytracesBmanyClittleDmuch7IntheUK,onlydrugproductsandbiologicalmanufacturers(notA;exceptsomespecifiedantibiotics)wereinspectedbytheregulatoryauthorityforcompliancetoGMP.AAPIsBdrugCmanufacturersDOTCs答案:1D2D3C4C5A6A7A五、英译汉（共20分,每题5分）。1Thefourmostabundantelementsinlivingorganisms,intermsofthepercentageofthetotalnumberofatoms,arehydrogen,oxygen,nitrogen,andcarbon,whichtogethermakeupover99%ofthemassofmostcells.答案:四种含量最丰富的元素在生物体中的原子总数的百分比计算，是氢，氧，氮，碳，加起来超过全部细胞总重的99％。2Aone-compartmentmodelwithfirst-ordereliminationoftenapproximatestheclinicalsituationsurprisinglywellonceabsorptionanddistributionhaveoccurred.试卷（A）共（5）页第（4）页答案:当吸收分布过程完成后，一个遵循一级消除的一室模型与临床情况十分相似。3Analyticalchemistsworktoimprovethereliabilityofexistingtechniquestomeetthedemandsforbetterchemicalmeasurementswhichariseconstantlyinoursociety.答案:分析化学家的工作是改善现有技术的可靠性，以更好的化学检测方法满足我们社会不断的需求。4Soliddrugproductsexemptedfromdisintegrationtestsincludetroches,tabletswhichareintendedtobechewed,anddrugproductsintendedforsustainedreleaseorprolongedorrepeataction.答案:免除崩解测试的固体药品包括含片、咀嚼片和缓控释释放、长效释放、重复释放制剂。六、问答题（共20分,每题5分）。1AccordingtotheNoyes-Whitneyequation,whatmaybeinfluencethedissolutionkinetics?答案:ItcanbeseenfromtheNoyes-Whitneyequationthatdissolutionkineticsmaybeinfluencedbythephysicochemicalcharacteristicsofthedrug,theformulation,andthesolvent.2Ifauthenticmaterialisnotavailable,whatshouldtobedoneforitsidentification？答案:Carefulcomparisonwithliteraturedatamanysufficeforitsidentification.3Whatistheselectivereactionortest?答案:Aselectivereactionortestisonethatcanoccurwithothersubstancesbutexhibitsadegreeofpreferenceforthesubstanceofinterest.4Whatistheaimofdrugdesign?答案:Dragdesignaimstoimprovethedesirableeffectsoftheleadcompoundandtoremovetheundesirableeffects.