一种心肌保护剂_磷酸肌酸

:侯立向(,100101)(phosphocreatine,PCr).1927(1930ATP),50.PCr2~30mmol/L.:ATP..,ATP,ATPPCr..(ANT),ATPPCr,,PCrATP(),ATPADP.PCrATP.,PCr:.,;,.PCr.,.,,,.,PCr.PCr.10mmol/LPCr,37CK69%,PCr;,PCr/.H2O2,,PCr.,()90mol/LH2O2,:20min;40minH2O2,,.,PCr()40min,.,,40minH2O2,.:H2O2,;,;,PCr,H2O2.PCr.PCr,,,;PCr(),,.PCr,.PCr(LPG).PCrLPG,PCrA2.PCrA2,,.LPG,PCrPCr.PCr,PCr:PCr,NR3+;PCr,NR3+.PCr,.PCr.:5min2ml/min,40min;15minPCr,5ml/min.PCr15?..,PCrADP,,.PCr.PCr,.PCr5-'.PCr,,.,PCr,ATPADP,.324Prog.Biochem.Biophys.2003;30(2)