分子印迹技术在样品前处理中的应用

12#1151025725106312005-12-022006-02-12No.031586No.2003C345031SPE70SPEC8C1811989BelardiSPMESPMESiO2SPESPME23SPME4～5MImolecularlyimprintedpolymerMIPSPESPMEMIPMIP2MIP--MIP3420067FENXIHUAXUEChineseJournalofAnalyticalChemistry71035～10416MIP7MIP30089MIP10～1233.1molecularlyimprinted-basedSolid-phaseextractionMIP1994SellergrenSPEMIP13MI-SPE1415SPEMI-SPEMIP50～500mg41MI-SPEMI-SPE1MI-SPE4Fig.1Fourproceedingsofmolecularimprintingsolid-phaseextractionMI-SPEMI-SPEMIPMIPMI-SPEMIPMIPMIP16MIPMIP17MIPMIP--1819202122630134MI-SPEmLGCHPLCMI-SPEHPLC23243.250%C18C18MIPMasque234-MIP4-MI-SPEHPLC4-MI-SPEBjarnason24MIPC18C18MIP100MI-SPEMI-SPEMullett25MI-SPEZander20MIPNMIPC18AnderssonMI-SPE-C18SPEMIPSPE18MIPMI-SPE15MIPSPE40nmol/L35.791.7%NMIPAndersson26MI-SPEsameridinesameridineMIP1MI-SPEMI-SPEMI-SPEMIPMIP5%41MI-SPEpg～ng1%MIP1826MIPMI-SPEMIP42MIPMIPMIP4MIPSPMEMIPSPMESPMEMI-SPME1MI-SPMEMIP730171MI-SPETable1Recentapplicationresearchesofmolecularimprinted-solidphaseextractionMI-SPESampleAnalytesMonomerPorogenSynthesismethodDetectionlimitRecovery%Ref.WaterMicrosystin-LRUrocanicacidethylesterDimethylSulphoxideBP350ng9827AqueoussamplesCocaineMAATolueneBP25µg/L7028WatersamplesPirimicarbMAAChloroformBP4.1µg/L/29RiverwaterPropazineMAATolueneBP100～200µg/L6730Riverwater245-Trichloro-phenoxyaceticacid4-4-VP-Methanol-water3:1V/VBP/94±531CaraganaJubataQuercetinAcrylamideTHFBP/7632PlasmaPhenytoinMAA-Acetoneitrile-THF76:24V/VBP/58～7833PlasmaandhumanurineTamoxifenMAAAcetonitrileBP600µg/L300µg/L95±3102±534UrineandplasmaScopolamineMAATolueneBP/46～5960～7935UrineFlameretardanthy-drolysisproduct2-2-VinylpyridineChloroformBP25µg/L7036Urine7-7-HydroxycoumarinMAAChloroformBP/90.37±7.3737HumanurinePhenobarbitalMAAChloroformSuspensionpolymerization/81～8638RedchilipowderⅠSudanⅠ4-4-VPChloroformBP/7039MilkSulfamethazineMAAAcetonitrileBP83.4µg/L10040BPBulkpolymerizationMAAMethacrylicacid4-VP4-VinylpyridineTHFTetrahydrofuranMullett43MI-SPMEβ-SPME0.32mg/LRSD5.0%MI-SPMEMI-SPMEMIPMIP442SPMEMIPSiO2MIPSiO2SPMEKoster45MIPSiO2brombuterolMIPMIPMIPMIPSPMESPMEMIP8301345346MIMMIMMIM1990Piletsky47Wang48MIPHong49MIMMIM-Petcu50MIM3min51245253545556MIMMIPMIMMIMMIMMIMMarx-Tibbon55-MIMMIMYang56-257Fig.2Molecularlyimprintedpolymermembranesbyphotograftcopolymerization57MIMPiletsky57MIM4Sergeyeva52MIMdometrynMIMMIM/1～2min93017612MIPMIP3MIPMIPMIPMIT-References1PichonVRogniauxHFischer-DurandNBenRejebSLeGofficFHennionM-C.Chromatographia199745289～2952WuJPawliszynJJ.J.Chromatogr.A200190937～523EisertRPawliszynJ.Anal.Chem.199769163140～31474WangZYXiaoCHWuCYHanHM.J.Chromatogr.A2000893157～1685GbatuTPSuttonKLCarusoJA.Anal.Chim.Acta19994021-267～796HuXiaogangTangYouwenHuangZhaofa.FineChemicals20052211～47FicherLMullerREkberBMosbachK.J.Am.Chem.Soc.1991113249358～93608KoeberRFleischerCLanzaFBoosKSSellergrenBBarceloD.Anal.Chem.200173112437～24449WhitcombeMJRodrihuezMEVillarPVulfsonEN.J.Am.Chem.Soc.1995117277105～711110RimmerS.Chromatographia1998477-8470～47411MotherwellWBBinghamMJSixY.Tetrahedron200157224663～468612HuXiaogangTangYouwen.JournalofSouthChinaNormalUniversityNaturalScience20031012154～16113SellergrenB.Anal.Chem.1994661578～158214LiuQinZhouYongxinMengZihuiWangQingqingHuXuyingLiuYintang.ChineseJ.Anal.Chem.2001294387～39015ZhouJieHanHongyanHeXiwenShiHuiming.ChineseJ.Anal.Chem.19992715～916SpivakDGilmoreMASheaKJ.J.Am.Chem.Soc.1997119194388～439317BerggrenCBayoudhSSherringtonDEnsingK.J.Chromatogr.A20008891-2105～11018AnderssonLI.Analyst200012591515～151719MartinPWilsonIDMorganDEJonesGRJonesK.Anal.Commun.19973445～4720ZanderAFindlayPRennerTSellergrenBSwietlowA.Anal.Chem.199870153304～331421LaiEPCWuSG.Anal.Chim.Acta20034811165～17422LaiEPCFengSY.MicrochemicalJournal2003753159～16823MasqueNMarceRMBorrullFCormackPAGSherringtonDC.Anal.Chem.200072174122～412624BjarnasonBChimukaLRamstromO.Anal.Chem.199971112152～215625MullettWMLaiEPC.Anal.Chem.19987013636～364126AnderssonLIPapricaAArvidssonT.Chromatographia199746257～6227ChianellaIPiletskySATothillIEChenBTurnerAPF.Bioelectron.200318119～12728ZurutuzaABayoudhSCormackaPAGDambiesaLDeereJBischoffRSherringtonDC.Anal.Chim.Acta200554214～1904013429MenaMLMartinez-RuizPReviejoAJPingarronJM.Anal.Chim.Acta20024512297～30430Carabias-MartínezRRodríguez-GonzaloEHerrero-HernándezE.J.Chromatogr.A20051085199～20631BaggianiCGiovannoliCAnfossiLTozziC.J.Chromatogr.A20019381-235～4432ZhuLLXuXJ.J.Chromatogr.A2003991151～15833BereczkiATolokanAHorvaiGHorvath-VVHallAJSellergrenB.J.Chromatogr.A20019301-231～3834RashidBABriggsRJHayJNStevensonD.Anal.Comm.19973410303～30535TheodoridisGKantifesAManesiotisPRaikosNTsoukali-PapadopoulouH.J.Chromatogr.A2003987103～10936MöllerKCrescenziCNilssonU.Anal.Bioanal.Chem.2004378197～20437WalsheMHowarthJKellyMTKennedyROSmythMR.J.Pharmaceut.Biomed.Anal.1997162319～32538HuSGWangSWHeXW.Analyst20031281485～148939PuociFGarreffaCIemmaFMuzzalupoRSpizzirriUGPicciN.FoodChemistry200593349～35340Guzmáan-VázquezdePradaAMartínez-RuizPReviejoAJPingarrónJM.Anal.Chim.Acta2005539125～13241CormackPAGMosbachK.React.Funct.Polym.1999411-3115～12442StevensonD.TrendsAnal.Chem.1999183154～15843MullettW