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DHA功效主要内容TOPICS一.DHA及其作用DHAanditseffects二.DHA对孕期的影响DHA’sinfluencetopregnancy三.DHA对婴幼儿的影响DHA’sinfluencetoinfants&kids四.纽曼斯TMDHA的优势NemansTMDHA’sadvantage什么是DHA?WhatisDHA?DHA是二十二碳六烯酸的缩写(n22:6),又称“脑黄金”“聪明因子”DHAistheabbreviationofDocoseHexaenoieAcid(n22:6),alsoknownas“BrainGold”“BrightnessGene”DHA属于Ω-3系列多不饱和脂肪酸是人体必需脂肪酸。DHAbelongstoΩ-3seriespolyunsaturatedacid,whichisessentialtoourbodies.人体无法自身合成;需要通过外界摄取,才能获得Itcan’tbesynthesizedbyhumanbodyandmustbeabsorbedfromdiet.长链n-3脂肪酸代谢LCPUFAmetabolism“DHA是人体内合成量最少的n-3LCPUFA”1DHAistheleastSyntheticn-3LCPUFAinhumanbody能量energyC前列腺素,血栓烷,白三烯,etc.Prostaglandins,thromboxane,Leukotrienes,etca-LAEPADHA在代谢通路上,由a-亚麻酸转化为n-3长链PUFA的效率逐渐降低Inmetabolism,theefficiencyofa-linolenicacidinton-3long-chainPUFAgraduallyreduceda-亚麻酸的作用更多的是提供能量而不是直接生物合成LCPUFAs.1a-linolenicacid'sroleistoprovideenergyratherthanadirectbiosynthesisofLCPUFAs.亚油酸Linoleic必需脂肪酸来自玉米油,芝麻油和葵花籽油Comefromcornoil,sesame&sunfloweroil来自亚麻籽油和豆油Comefromflaxseedoil&soybean深海鱼亚麻酸在人体内可以转化为DHA。研究表明,人体只能将0.01-5%的ALA转化为DHA。LinolenicacidcanbeconvertedintoDHAinhumanbody.Studieshaveshownthathumanbodycanonlyconvert0.01%-5%ofALAtoDHA.亚麻酸LinolenicEssentialFattyAcidDeepseafishDHA存在于人体的各部位:DHAExistsinVariousBodyParts大脑:占大脑脂质10%,是大脑灰质中脂肪的主要成分,占n-3不饱和脂肪酸97%Brain:Accountedfor10%ofbrainlipid,isthemaincomponentoffatinthebraingreymatter,97%ofn-3polyunsaturatedfattyacid视网膜:占n-3不饱和脂肪酸93%Retina:93%ofn-3polyunsaturatedfattyacid心脏:重要组分Heart:Majorcompositionofheartissue母乳:天然存在BreastMilk:Naturallyconsisted1432DHA对整个生命阶段的作用DHA’srolethroughoutlife对孕妇而言¤促进孕期健康¤减少产后抑郁症的发生几率¤增加母乳中DHA的含量对儿童和成年人而言心脏健康¤降低甘油三酸酯¤增加高密度脂蛋白对婴幼儿而言¤大脑和视力发展和功能¤提高视力敏锐度¤提高认知能力对成年人¤维护正常认知能力¤降低患痴呆症的风险¤降低老年黄斑变性的风险DHA对孕期的影响DHA’sInfluencetoPregnancy孕妇血细胞中DHA比例图TheproportionofDHAinmaternalbloodcells100%62%40%38%0%10%20%30%40%50%60%70%80%90%100%正常妇女NormalWoman怀孕期Pregnancy分娩期Confinement哺乳期Lactation母体缺乏DHAMotherlackofDHA智力IQ视力Sight6周8周From25thweekofpregancy,DHAgathersrapidlyinfetal’sbrainDHA对孕妈咪的作用DHA’seffecttopregnancy怀孕期间,若母体缺乏DHA,会影响胎儿的脑细胞和视网膜的生长和发育Mother’slackofDHAinpregnancywillinfluencefetal’sbraincell&retinadevelopment促进胎儿脑细胞和视网膜的生长发育helptodevelopeinfants’braincells&retina能改善产后抑郁症alleviatepostpartumdepression延长具有早产风险的妇女妊娠期extendgestationtimeforthemotherswhohaveabortionrisk降低心血管带来的风险,降低心率不齐的发生Reducecardiovascularrisk,reduceirregularheartbeats相关资料Relatedinfo.DHA对孕妈咪的作用DHA’seffecttopregnancy母乳喂养婴儿的成人患糖尿病的比率比较低,主要由于DHA水平也参与控制胰岛素的能力,避免发生肥胖症。Breastfeedingrateofadultdiabetesisrelativelylow,mainlybecauseDHAlevelsareinvolvedincontrollinginsulin,toavoidOBESITY.DHA对婴幼儿的重要性DHA’simportancetoinfants&kids胎脑发育的顺序为:Fetalbraindevelopmentprocess:孕8-20周,是神经母细胞增殖8th-20thweekofpregnancy,neuroblastomaproliferation第25周-40周是早期母细胞分化,25th-40thweekofpregnancy,earlyblastomadifferentiation孕20周-出生后2年是神经胶质细胞增殖,20thweekofpregnancy-2yearsold,Glialcellsproliferation出生-4岁是晚期母细胞分化,Birth-4yearsold,lateblastomadifferentiation孕25周-6岁是髓鞘形成25thweekofpregnancy-6yearsold,myelinizationInfetalperiod,neuronsincreaseat250000/min出生时脑细胞数已达1千亿个,为满足这一时期生长的需要,必须供给充足的营养物质。Humanhave100billionbraincellsattheirbirth,andneedadequatenutrientsfordevelopment.DHA对胎儿、婴幼儿的重要性DHA’simportancetofetals,infants&kids婴儿从出生时脑重量为400g到1400g,增加的联结神经细胞的网络,而网络主要是由脂质构成,其中DHA量可达10%。DHA对脑神经的传导和突触的生长发育起着重要的作用。DHAplaysanimportantroleinthecranialnerveconductionandsynapticdevelopment.DHA对胎儿、婴幼儿的重要性DHA’simportancetofetals,infants&kids足量的DHA添加可以促进婴儿脑部发育,并表现出认知、记忆、语言、解决困难能力、辨别能力、社会能力等高级神经功能的全面提升。出生后的婴幼儿如不能获得充足的DHA,则脑发育过程会延缓或受阻,智力发育将受到影响,还可造成宝宝视网膜发育不全DHA对胎儿婴幼儿的作用DHA’seffecttofetals,infants&Kids可以改善脂肪酸营养状况,改善视觉功能,学习能力,使宝宝体重,身长和头围达到正常水平,视力和智力发育更好DHA对早产儿,双胞胎多胞胎的作用DHA’seffecttoprematurechildren,twins&multiplebirths孕期补充DHA妇女其血浆和乳汁中以及其新生儿脐血中DHA含量的观察上海交通大学医学院附属新华医院上海市儿科医学研究所研究目的PurposeofStudy观察妊娠期妇女在孕期补充DHA后,对她血浆和乳汁中以及她分娩的新生儿脐血中DHA含量的影响。方法Method选择健康孕妇60例,随机分为二组:Select60healthypregnancys,divideintotwogroupsrandomly:DHA补充组,共40例孕妇,年龄26±2岁,自怀孕20周起每天补充DHA约110mg,一直至分娩。DHAsupplygroup,40pregnancys,age26±2yearsold,takeabout110mgDHAperdayafter20weeksofpregnancyuntillchildbirth.对照组,孕妇20例,年龄相仿,在孕期不添加DHA。Contrastgroup,20pregnancys,familiarage,don’ttakeDHAduringpregnancy.测试时间TestTime两组孕妇在怀孕20周,30周及分娩时分别测定她血浆中的DHA以及其他各种脂肪酸的含量,Testbothgroups’DHA&otherfattyacidslevelinplasmaat20th,30thoftheirpregnancyandatchildbirth.同时也测定该二组孕妇分娩的新生儿脐血中DHA及其他各种脂肪酸的含量,以及孕妇分娩后其乳汁中DHA的含量。AlsotesttheDHA&otherfattyacidslevelincordbloodoftheirnewbirthandtheDHAlevelintheirbreastmilk.结果1:血浆中Result1:inplasma组别Group孕20周20thweek孕30周30thweek分娩时childbirth添加DHA组DHAgroup2.73±0.54%3.70±1.14%3.48±1.16%对照组Contrastgroup2.73±0.54%2.77±0.812.95±0.83结果2:新生儿脐血中DHA的浓度Result2:DHAConcentrationincordbloodofnewbirthDHA添加组DHAgroup7.49±2.17%对照组Contrastgroup5.86±2.15%结果3:母乳中DHA的含量Result3:DHAcontentinbreastmilkDHA添加组DHAgroup0.72±0.47%对照组Contrastgroup0.42±0.16结果Result研究表明妊娠期妇女孕期补充DHA,可使其血浆和母乳中以及其分娩的新生儿脐血中DHA含量显著增加。实验表明,母亲在孕期额外补充DHA,对胎儿和婴幼儿的大脑和视网膜的发育有促进作用。n-3不饱和脂肪酸抗抑郁效果双盲安慰剂对照实验的meta-分析法double-blind,placebo-controlledtrialstostudyanti-depressanteffectofn-3polyunsaturatedfattyacidsmeta-analysismethod临床研究ClinicalResearch孕期补充DHA减少产后抑郁的发生率SupplyDHAduri
本文标题:DHA功效
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