老年机械通气患者铜绿假单胞菌药敏分析

,,(,100853):200216,20021630943263,(Kirby2Bauer)66.9%;47.1%44.7%;45%;43%;40.4%;39.2%;87%100%,40%:;;;:R378.99+1:A:100524529(2003)0320278202PseudomonasaeruginosaInfectionintheElderlyPatientswithMechanicalVentilation:AnAnalysisofDrugSensitivityTestsZHANGXiao2jun,LIUChang2ting,ZHANGJun2min(GeneralHospitalofPLA,Beijing100853,China)Abstract:OBJECTIVEToanalysethedrugsensitivityof16kindsantibioticsintheelderlypatientswithmechan2icalventilationin2002inordertoinstructcliniciansusingthemmorereasonable.METHODSToanalysedrugsensitivityof94strainsofPseudomonasaeruginosain30caseswithtrachealincisionand63strainsofP.aerugi2nosain32caseswithtrachealcannula.RESULTSThesensitivityratesofP.aeruginosatoamikacinwas66.9%;tomeropenem47.1%;imipenem44.7%;ceftazidime45%;cefepime43%;piperacillin40.4%;ciprofloxacin39.2%;andtocefoperazoneösulbactam38%;itsrestistanceratetocefotaxime,trimethoprim,chloramphenicol,azithromycinwasfrom87%to100%.CONCLUSIONSMostantibioticswereresistanttoP.aeruginosaintheel2derlypatientswithmechanicalventilation.Antibioticsofmorethan40%sensitivityrateswereamikacin,meropenem,ceftazidime,imipenem,cefepimeandpiperacillin.Keywords:Pseudomonasaeruginosa;Drugsusceptibility;Trachealcannula;Tracheostomy,,,,,,70%16215716,200211.132,30COPD:2002207220;:2002212211,1,1,,3581d,32,6692,(74.55.32)30,25COPD,13130,6888,(76.125.82)1.2,1.3,262157872ChinJNosocomiolVol.13No.3200366.9%;47.1%44.7%;45%;43%;40.4%;39.2%34.2%;ö38%,25.3%,87%100%1115716(%)nS%I%R%512447.135.92447.11502244.7503.37852.01516845.085.37549.715100.01912.613287.41503825.32214.79060.01516543.02315.26341.7ö1505738.03523.35838.71503724.72919.38456.01516140.400.09059.61485839.22516.96543.91495134.2128.18657.715110166.92113.92919.21485738.52919.66241.915132.010.714797.414321.453.513695.113732.21410.212087.63,,,,,48%,B22,,,98.6%;97.8%;97.4%,,90%3:;;;;;,419962000:(44.7%;70.9%)(45%;57.29%)(40.4%;44.56%)(39.2%;51.58%)(38%;48%)(24.7%;24.78%),2002:;;;(10d),66.9%,16,(),(),,,,9%,1.3%5:1.[J.,1989,12(2):82283.2.[J.,1996,1(14):32233.3HolyeBD,JassJ,CostertonJW.Thebiofilmglycocalysasaresistancefactor[J.AntimicrobChemother,1990,26:4732478.4,,,.[J.,2002,12(6):4192421.5,,.[J.,2000,4(10):3092310.9722003133