表面增强拉曼光谱在环境分析中的研究进展

0，。，，10-10，。1974，Fleischmann[1]，，。1977，JeanmaireVanDuyne[2]，，6，，（SERS）。SERS，、、、[3~5]。SERS，SERS，：SERS；SERS、、；SERS，，，*，Tel:[phone],E-mail:[e-mail]*，，（，410082）：（SERS）,1014~1015。，，，，，，。SERS，SERS。，SERS。：；；Recentadvancementsinenvironmentalanalysisbasedonsurface-enhancedRamanspectroscopyGongJi-lai*,LvPu,ZengGuang-ming(CollegeofEnvironmentalScienceandEngineering,HunanUniversity,Changsha410082,China)Abstract:Surface-enhancedRamanscatteringisanunusualsurfaceopticalphenomenonandtheenhancementfactorisupto1014~1015.Environmentalpollutiongreatlyinfluencesthehumansurvivals.Itisnecessaryforustotakemoresensitivemethodstodetectenvironmentalpollutantssuchaspersistentorganicpollutants,whicharelowlevel,hightoxicityandhardtobedetected.SERStechnologyhasthepotentialtobecomeanexceedinglysensitivetoolfortheanalysisofenvironmentalpollutantsduetoitshighsensitivity.Thisarticlerevieweddevelopmenttrendsinenvironmentalanalysisusingsurface-enhancedRamanspectroscopytechnologyandthepotentialapplicationofSERSsensor.Keywords:surface-enhancedRamanscattering;sensor;environmentalanalysisVol．29,No．3Sept．2009CHEMICALSENSORS29320099[6]。，、SERS；SERS；SERS。。（）SERS。，SERS、、、、、、[7]。SERS，SERS[8~9]。SERS，SERS[10]。[11]SERS，。[12~16]SERS。SERS，、SERS。，，，SERS。，SERSDNA，，[17]。1995，Vo-DinhSERS[18]。2006，KneippSERS[19]。2008，ZhaoSERS、，[20]。，，，（POPs），，，，，。，，，，[21]，1014~1015，，，、、、、[22~24]。。1，，。。、、、、、、、、。10-12~10-9g/L，，。2004，Schmidt[25]SERS。SERS－，，μg/Lng/L。1200NTU。2006，Sanchez-Cortes[26]，SERS，10-9mol/L。－π－π，－3.4魡，/。2008，Campos-Vallette[27]SERS。，Sanchez-Cortes[28]SERS。。。，Sanchez-Cortes[29]SERS，、、。2009，Guerrini[30]：39SERS。Guerrini，：、。，、，SERS10-9mol/L，（）zmol。，SERS，，。，Haynes[17]SERS。/（AgFON），，AgFONSERS。SERS，2.5×106，SERS300pmol/L700pmol/L。2、、，，。，。。2003，Shende[31]，mg/L。2004，Shende[32]。2006，Lee[33]，0.1mg/L。2008，Sanchez-Cortes[34]－，－－SERS，，20μg/L。，Strickland[35]，。，SERS50μmol/L。3。2002，Mirkin[36]SERS，A、B、、、Bacillusanthracis。2005，VanDuyne[37]SERS。，Porter[38]。2008，Kahraman[39]、、，。2008Jarvis[40]，Geobactersulfurreducens。，Porter[41]。4。[42]，－//－，Cu2+。。Gu[43]。Haynes[44]。Mosier-Boss[45]。[46]。5，，。、2910，，，，SERS。[1]FleischmannM,HendraPJ,McQuillanA.Ramanspec-traofpyridineadsorbedatasilverelectrode[J].Chemi-calPhysicsLetters,1974,26(2):163~166.[2]JeanmaireDL,VanDuyneRP.SurfaceRamanspectro-electrochemistryPartI.Heterocyclic,aromatic,andaliphaticaminesadsorbedontheanodizedsilverelec-trode.JournalofElectroanalyticalChemistry[J].1977,84(1):1~20.[3]LeeYH,FarquharsonS,RaineyP.Surface-enhancedRamansensorfortracechemicaldetectioninwater[C].ChemicalMicrosensorsandApplicationsII,1999,3857:76~84.[4]Vi-DinhT,YanF,WabuyeleMB.Surface-enhancedRamanscatteringforbiomedicaldiagnosticsandmolecu-larimaging[J].TopicsinAppliedPhysics,2006,103:409~427.[5]GrahamD,GoodacreR.Chemicalandbioanalyticalap-plicationsofsurfaceenhancedRamanscatteringspec-troscopy[J].ChemicalSocietyReviews,2008,37:883～884.[6]TianZQ.Surface-enhancedRamanspectroscopy:ad-vancementsandapplications[J].JournalofRamanSpectroscopy,2005,36:466～470.[7]TianZQ,YangZL,RenB,etal.SERSfromtransitionmetalsandexcitedbyultravioletlight[J].TopicsinAp-pliedPhysics,2006,103:125～147.[8]QianXM,NieSM.Single-moleculeandsingle-nanoparticleSERS:fromfundamentalmechanismstobiomedicalapplications[J].ChemicalSocietyReviews,2008,37:912~920.[9]KneippK,KneippH,BohrHG,Single-moleculeSERSspectroscopy[J].TopicsinAppliedPhysics,2006,103:261~278.[10]PorterMD,LipertRJ,SiperkoLM,etal.SERSasabioassayplatform:fundamentals,design,andapplications[J].ChemicalSocietyReviews,2008,37:1001~1011.[11]QianX,PengXH,AnsariDO,etal.Invivotumortar-getingandspectroscopicdetectionwithsurface-en-hancedRamannanoparticletags[J].NatureBiotechnol-ogy,2008,26:83~90.[12]GongJL,JiangJH,LiangY,etal.Synthesisandcharac-terizationofsurface-enhancedRamanscatteringtagswithAg/SiO2core-shellnanostructuresusingreversemi-celletechnology[J].JournalofColloidandInterfaceScience,2006,298:752～756.[13]GongJL,JiangJH,YangHF,etal.Noveldye-embed-dedcore-shellnanoparticlesassurface-enhancedRa-manscatteringtagsforimmunoassay[J].AnalyticaChimicaActa,2006,564:151～157.[14]GongJL,LiangY,HuangY,etal.Ag/SiO2core-shellnanoparticle-basedsurface-enhancedRamanprobesforimmunoassayofcancermarkerusingsilica-coatedmag-neticnanoparticlesasseparationtools[J].BiosensorsandBioelectronics,200722:1501～1507.[15]LiangY,GongJL,HuangY,etal.Biocompatiblecore-shellnanoparticle-basedsurface-enhancedRamanscat-teringprobesfordetectionofDNArelatedtoHIVgeneusingsilica-coatedmagneticnanoparticlesasseparationtools[J].Talata,2007,72:443～449.[16]ChenJW,JiangJH,GaoX,etal.Gold-aggregated,dye-embedded,polymer-protectednanoparticles(GDPNs):anewtypeoftagsfordetectionwithSERS[J].ColloidsandsurfacesA:PhysicochemicalandEngineer-ingAspects,2007,294:80～85.[17]JonesCL,BantzKC,HaynesCL.Partitionlayer-modi-fiedsubstratesforreversiblesurface-enhancedRamanscatteringdetectionofpolycyclicaromatichydrocarbons[J].AnalyticalandBioanalyticalChemistry,2009,394:303～311.[18]Vo-DinhT.SERSchemicalsensorsandbiosensors:newtoolsforenvironmentalandbiologicalanalysis[J].Sen-sorsandActua