废水处理中群体感应调控行为研究进展李松亚

112*1333130007223003843300384．、、．、．、、、．Progressontheregulationofquorumsensinginwastewatertreatment．LISong-ya1FEIXue-ning12*JIAOXiu-mei13WANGLe3XINGYan-jun31SchoolofEnvironmentalScienceandEngineeringTianjinUniversityTianjin300072China2SchoolofSicenceTianjinChengjianUniversityTianjin300384China3SchoolofMunicipalandEnvironmentalEngineeringTianjinChengjianUniversityTianjin300384China．AbstractQuorumsensingisaphenomenonthatmicroorganismssecretesomesignalmoleculeswhensuchmoleculesaccumulatetoathresholdlevelwhichwouldrealizetheinformationcommuni-cationbyregulatingspecificgeneexpression．Quorumsensingwhichiswidelyfoundininformationcommunicationofvariousmicroorganismsregulatesavarietyofsocialbehaviorssuchasbiofilmformationpublicgoodsproductionandgenehorizontaltransferofbacteria．Thephenomenonofquorumsensingiswidespreadinbiologicalaggregatessuchasactivatedsludgebiofilmandgranu-larsludge．Learningandunderstandingtheregulationbehaviorbetweenquorumsensingandmicro-organismsplaysanimportantroleinwastewatertreatment．Herewereviewedtheclassificationofthesensingsignalmoleculeregulationmechanismofquorumsensingaswellastheregulationbehaviorofquorumsensinginactivatedsludgebiofilmaerobicgranularsludgeandanaerobicgranularsludge．Thefutureresearchesofquorumsensinginwastewatertreatmentwerediscussed．Thisreviewcoulddeepentheunderstandingoftheregulationofquorumsensinginwastewatertreatment．Keywordsquorumsensingsensingsignalmoleculeregulationbehaviorwastewatertreatment．515783605177839815ZCZDSF00150ThisworkwassupportedbytheNationalScienceFoundationofChina5157836051778398andTian-jinScienceandTechnologyPlanProject15ZCZDSF00150．2017-08-02Received2017-12-26Accepted．*[e-mail]．．1979Nealson1VibriofiscberiquorumsensingQS．2－3．45．20183293http//．cjae．netChineseJournalofAppliedEcologyMar．20182931015－1022DOI10．13287/j．1001－9332．201803．036、、、、6－8．Davies9《Science》McLean10AHLs．Valle11AHLsAHLs．Ren12．、、13－17．．、、．11979“”．．318N-N-acylhomoserinelactonaseAHLs-1autoinducingpeptideAIPs-2autoinducer-2AI-2．PQS、DSF-3AI-3．1．2LuxI/R．AHLs、AHLsLuxI、AHLsLuxR．AHLs24AHLsLuxIAHLsAHLsLuxRLuxR．EPS、、19－20．AIPsAIPsAHLsABCATP-bindingcassette．AHLsAIPs/18．AIPs3．AI-21Fig．1Structureofvarioussensingmolecules．AN-N-acylhomoserinelactonaseAHLsBAI-2AI-2isolatedfromVibriofiscberiCAI-2AI-2isolatedfromSalmonellaD、E、F、GAIPsDifferentkindsofautoinducingpeptideAIPs．6101292AHLs4Fig．2SchematicdiagramofAHL-typequorumsensingmecha-nism4．ALowcelldensityBHighcelldensity．Thesamebelow．3AIPs4Fig．3SchematicdiagramofAIPs-typequorumsensingmecha-nism4．AI-2．AI-2LuxSLuxSAI-221．S-SAMS-SAH5'-/S-PfsSRHLuxS45--23-DPDDPDAI-222－23．AI-2．AI-2LuxP/LuxQ．、AI-2LuxQLuxU424Fig．4RegulationmechanismofVibrioharveyiquorumsen-sing24．LuxOLuxRAI-2LuxPLuxQLuxOLuxR24．4．33.125426－27．Valle11AHLsMorgan-Sagastume28、AHLsAHLsAero-monasspp．Pseudomonasspp．．Chong29AHLs．．．Valle112μmol·L－1AHLsYongZhong30PseudomonasaeruginosaCGMCC1．860、、、AHLsAHLs71013AHLsAHLs．．YongZhong31rhlHuang32．．Burton33NitrosomonaseuropaeaSchmidtC6-HSL、C8-HSLC10-HSL3Li13AHLs3-oxo-C6-HSLC6-HSL．Mellbye34NitrobacterwinogradskyiNO、NO2N2O．．．3.2ParsekGreenberg35．．Shrout36．lasrhl37．．EPSEPS．Bacillussubti-lis38Vibriocholera39EPS．AHLs．Lade40AHLs．Hu41AHLsAHLsEPS．、、、42．．、．．Yeon43．XuLiu4424-ATPAI-2EPS．Kim45EPS．Kim46MBRCEBsCEBsEPSMBR．Nam47CV026．3.3．Ren12．AI-2AHLs．XiongLiu48AI-2810129AI-2．AI-2．AI-2AI-2EPS1449．Zhang50SBRAI-2AI-2DPD．AI-2AI-2．AI-2AHLs．AHLsAHLsEPS．JiangLiu51AHLsAHLsEPS．Tan52AHLsEPS．Ren53AHLs．Ren53AHLsEPSEPS．AHLsAHLsAHLs．AHLsEPS．Lv54KAHLs．LiZhu55AHLsAHLsAHLs．3.4．．56、．Feng57．Ding583AI-2EPS、AHLsAI-2DSF、．Ding1659pHAI-2DSFAI-2DSF．Li60AHLsUASB．．4、、．．1291013AHLsAIPs3AHLs45．．．、、．1NealsonKHHastingsJW．BacterialbioluminescenceItscontrolandecologicalsignificance．MicrobiologicalReviews197943496－5132DechoAWFreyRLFerryJL．ChemicalchallengestobacterialAHLsignalingintheenvironment．ChemicalReviews201111186－993LaiB-MWangM-ZShenD-S．BacterialquorumsensingCooperationandcheating．ChineseJournalofAppliedEcology20172851735－1742inChinese4ShroutJDNerenbergR．MonitoringbacterialtwitterDoesquorumsensingdeterminethebehaviorofwaterandwastewatertreatmentbiofilmsEnvironmentalScienceandTechnology2012461995－20055CherninLToklikishviliNOvadisMetal．Quorum-sensingquenchingbyrhizobacterialvolatiles．Environ-mentalMicrobiologyReports20113698－7046DengYYWuJETaoFetal．ListeningtoanewlanguageDSF-basedquorumsensingingram-negativebacteria．ChemicalReviews2011111160－1737HouB-LLiA-JSunQ．TheeffectofN-acy-homoserinelactonesmediatedquorum-sensingontheadhesiongrowthandnitrificationofnitrifyingsludge．ActaScientiaeCircumstantiae20153592773－2779inChinese8LyuM-LZhuLDaiXetal．Effectsofextracellularproteinontheforma-tionandpropertiesofmicrobialassemblagesAreview．ChineseJournalofAppliedEcology2013243878－884inChinese9DaviesDGParsekMRPearsonJPetal．Theinvolve-mentofcell-to-cellsignalsinthedevelopmentofabacterialbiofilm．Science1998280295－29810McleanRJWhiteleyMSticklerDJetal．Evidenceofautoinduceractivityinnaturallyoccurringbiofilms．FEMSMicrobiologyLetters1997154259－26311ValleABaileyMJWhiteleyASetal．N-acyl-L-homo